ELISA Kit for Rat Urokinase-type plasminogen activator

Mfr.No.	E0140r
Categories	Elisa
Function	Specifically cleave the zymogen plasminogen to form the active enzyme plasmin.
Specificity	Natural and recombinant Rat Urokinase-type plasminogen activator
Subcellular Location	Secreted
Detection Range	15.6-1000pg/mL
Entryname	UROK_RAT
Method Type	Sandwich
Platform	PF00051
Protein Name	Urokinase-type plasminogen activator
Sensitivity	7.87pg/mL
Sequence	50: MRVWLASLFL ; CALVANSEGG ; SELEASDESN ; CGCQNGGVCV ; SYKYFSSIRR ; 100: CSCPKKFKGE ; HCEIDTSKTC ; YHGNGQSYRG ; KANTDTKGRP ; CLAWNSPAVL ; 150: QQTYNAHRSD ; ALSLGLGKHN ; YCRNPDNQRR ; PWCYVQIGLK ; QFVQECMVQD ; 200: CSLSKKPSST ; VDQQGFQCGQ ; KALRPRFKIV ; GGEFTVVENQ ; PWFAAIYLKN ; 250: KGGSPPSFKC ; GGSLISPCWV ; ASATHCFVNQ ; PKKEEYVVYL ; GQSKRNSYNP ; 300: GEMKFEVEQL ; ILHEDFSDET ; LAFHNDIALL ; KIRTSTGQCA ; QPSRTIQTIC ; 350: LPPRFGDAPF ; GSDCEITGFG ; QESATDYFYP ; KDLKMSVVKI ; ISHEQCKQPH ; 400: YYGSEINYKM ; LCAADPEWKT ; DSCSGDSGGP ; LICNIDGRPT ; LSGIVSWGSG ; 432: CAEKNKPGVY ; TRVSYFLNWI ; QSHIGEENGL ; AF
Sequence Length	432
String	P29598
Sub Unit	Found in high and low molecular mass forms. Each consists of two chains, A and B. The high molecular mass form contains a long chain A which is cleaved to yield a short chain A. Binds LRP1B; binding is followed by internalization and degradation. Interacts with MRC2. Interacts with PLAUR.

Reference	1. "Transcriptional and posttranscriptional activation of urokinase plasminogen activator gene expression in metastatic tumor cells." Henderson B.R., Tansey W.P., Phillips S.M., Ramshaw I.A., Kefford R.F. Cancer Res.52:2489-2496(1992) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Fischer 344. 2. Rabbani S.A. Submitted (1992-04) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Kidney. 3. "The receptor for the plasminogen activator of urokinase type is up-regulated in transformed rat thyroid cells." Ragno P., Cassano S., Degen J., Kessler C., Blasi F., Rossi G. FEBS Lett.306:193-198(1992) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 31-62;IDENTIFICATION OF UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR BINDING DOMAIN

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