ELISA Kit for Rat Urokinase plasminogen activator surface receptor

Mfr.No.	E0141r
Alternative Names	CD87
Categories	Elisa
Function	Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA.
Specificity	Natural and recombinant Rat Urokinase plasminogen activator surface receptor
Subcellular Location	Isoform 2 Secreted
Detection Range	78-5000pg/mL
Entryname	UPAR_RAT
Method Type	Sandwich
Platform	PF00021
Protein Name	Urokinase plasminogen activator surface receptor
Sensitivity	39pg/mL
Sequence	50: MGLLRRRLLL ; LVVVVTTCVP ; ASQGLRCIQC ; ESNQDCLVEE ; CALGQDLCRT ; 100: TVLREWEDAE ; ELEVVTRGCA ; HKEKTNRTMS ; YRMGSVIVSL ; TETVCATNLC ; 150: NRPRPGARGR ; PFPRGRYLEC ; ASCTSLDQSC ; ERGREQSLQC ; RYPTEHCIEV ; 200: VTLQSTERSV ; KDEPYTKGCG ; SLPGCPGTAG ; FHSNQTFHFL ; KCCNFTQCNG ; 250: GPVLDLQSLP ; PNGFQCYSCE ; GNSTFGCSYE ; ETSLIDCRGP ; MNQCLEATGL ; 300: DVLGNRSYTV ; RGCATASWCQ ; GSHVADSFQT ; HVNLSISCCN ; GSGCNRPTGG ; 328: APGPGPAHLI ; LIASLLLTLR ; LWGIPLWT
Sequence Length	328
String	P49616
Sub Unit	Monomer (Probable). Interacts (via the UPAR/Ly6 domains) with SRPX2. Interacts with MRC2.

Reference	1. "Isolation and characterization of multiple isoforms of the rat urokinase receptor in osteoblasts." Rabbani S.A., Rajwans N., Achbarou A., Murthy K.K., Goltzman D. FEBS Lett.338:69-74(1994) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2) tissue: Osteoblast. 2. DeYoung M.B., Wohlgemuth J., Dichek D.A. Submitted (1997-06) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1) strain: Sprague-Dawley. tissue: Aortic smooth muscle. 3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1) tissue: Thymus. 4. "The receptor for the plasminogen activator of urokinase type is up-regulated in transformed rat thyroid cells." Ragno P., Cassano S., Degen J., Kessler C., Blasi F., Rossi G. FEBS Lett.306:193-198(1992) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INDUCTION

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