Inhibits the dipeptidyl peptidase activity of DPP4 (By similarity). Cell surface proteoglycan that bears heparan sulfate. May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs. May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. May regulate growth and tumor predisposition.
Specificity
Natural and recombinant Rat Glypican-3
Subcellular Location
Cell membrane Lipid-anchor GPI-anchor Extracellular side Secreted