ELISA Kit for Rat Gamma-synuclein

Mfr.No.	E1271r
Alternative Names	Persyn ; Sensory neuron synuclein
Categories	Elisa
Function	Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway.
Specificity	Natural and recombinant Rat Gamma-synuclein
Subcellular Location	Cytoplasm perinuclear region Cytoplasm cytoskeleton centrosome Cytoplasm cytoskeleton spindle Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle.
Detection Range	0.312-20ng/mL
Entryname	SYUG_RAT
Method Type	Sandwich
Platform	PF01387
Protein Name	Gamma-synuclein
Sensitivity	0.172ng/mL
Sequence	50: MDVFKKGFSI ; AREGVVGAVE ; KTKQGVTEAA ; EKTKEGVMYV ; GTKTKGERGT ; 100: SVTSVAEKTK ; EQANAVSEAV ; VSSVNTVATK ; TVEEAENIVV ; TTGVVRKEDL ; 123: EPPAQDQEAK ; EQEEGEEAKS ; GGD
Sequence Length	123
String	Q63544
Sub Unit	May be a centrosome-associated protein.

Reference	1. "Peripheral nervous system-specific genes identified by subtractive cDNA cloning." Akopian A.N., Wood N. J. Biol. Chem.270:21264-21270(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Sprague-Dawley. tissue: Spinal ganglion. 2. "Gamma synuclein is expressed in the hippocampus of adult rats." Klugmann M., Leichtlein C.B., During M.J. Submitted (2004-01) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Wistar. tissue: Brain. 3. Lubec G., Afjehi-Sadat L. Submitted (2006-11) to the UniProtKB [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 81-96;IDENTIFICATION BY MASS SPECTROMETRY strain: Sprague-Dawley. tissue: Spinal cord. 4. "Persyn, a member of the synuclein family, has a distinct pattern of expression in the developing nervous system." Buchman V.L., Hunter H.J., Pinon L.G., Thompson J., Privalova E.M., Ninkina N.N., Davies A.M. J. Neurosci.18:9335-9341(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY

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BHE13810016	E1271r	96T	$796		Add to Cart