ATP-binding cassette sub-family B member 3 ; Abcb3 ; Mtp2
Categories
Elisa
Function
Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. Also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin.
Specificity
Natural and recombinant Rat Antigen peptide transporter 2
Subcellular Location
Endoplasmic reticulum membrane Multi-pass membrane protein The transmembrane segments seem to form a pore in the membrane.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS TAP2L PHE-352 AND ARG-603