ELISA Kit for Mouse Urokinase-type plasminogen activator

Mfr.No.	E0140m
Categories	Elisa
Function	Specifically cleave the zymogen plasminogen to form the active enzyme plasmin.
Specificity	Natural and recombinant Mouse Urokinase-type plasminogen activator
Subcellular Location	Secreted
Detection Range	93.75-6000pg/mL
Entryname	UROK_MOUSE
Method Type	Sandwich
Platform	PF00051
Protein Name	Urokinase-type plasminogen activator
Sensitivity	46.875pg/mL
Sequence	50: MKVWLASLFL ; CALVVKNSEG ; GSVLGAPDES ; NCGCQNGGVC ; VSYKYFSRIR ; 100: RCSCPRKFQG ; EHCEIDASKT ; CYHGNGDSYR ; GKANTDTKGR ; PCLAWNAPAV ; 150: LQKPYNAHRP ; DAISLGLGKH ; NYCRNPDNQK ; RPWCYVQIGL ; RQFVQECMVH ; 200: DCSLSKKPSS ; SVDQQGFQCG ; QKALRPRFKI ; VGGEFTEVEN ; QPWFAAIYQK ; 250: NKGGSPPSFK ; CGGSLISPCW ; VASAAHCFIQ ; LPKKENYVVY ; LGQSKESSYN ; 300: PGEMKFEVEQ ; LILHEYYRED ; SLAYHNDIAL ; LKIRTSTGQC ; AQPSRSIQTI ; 350: CLPPRFTDAP ; FGSDCEITGF ; GKESESDYLY ; PKNLKMSVVK ; LVSHEQCMQP ; 400: HYYGSEINYK ; MLCAADPEWK ; TDSCKGDSGG ; PLICNIEGRP ; TLSGIVSWGR ; 433: GCAEKNKPGV ; YTRVSHFLDW ; IQSHIGEEKG ; LAF
Sequence Length	433
String	P06869
Sub Unit	Found in high and low molecular mass forms. Each consists of two chains, A and B. The high molecular mass form contains a long chain A which is cleaved to yield a short chain A. Binds LRP1B; binding is followed by internalization and degradation. Interacts with MRC2. Interacts with PLAUR.

Reference	1. "Cloning, nucleotide sequencing and expression of cDNAs encoding mouse urokinase-type plasminogen activator." Belin D., Vassalli J.-D., Combepine C., Godeau F., Nagamine Y., Reich E., Kocher H.P., Duvoisin R.M. Eur. J. Biochem.148:225-232(1985) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "The murine urokinase-type plasminogen activator gene." Degen S.J.F., Heckel J.L., Reich E., Degen J.L. Biochemistry26:8270-8279(1987) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] 3. "Structure-based engineering of species selectivity in the interaction between urokinase and its receptor: implication for preclinical cancer therapy." Lin L., Gardsvoll H., Huai Q., Huang M., Ploug M. J. Biol. Chem.285:10982-10992(2010) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS) OF 21-154 IN COMPLEX WITH PLAUR;DISULFIDE BONDS

Have you used this product?

SKU	Supplier No.	Size	Your price	Quantity
BHE13811529	E0140m	96T	$776		Add to Cart