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ELISA Kit for Mouse Thrombopoietin

SKU : BHE13812005

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0135m
Alternative Names	C-mpl ligand ; ML ; Megakaryocyte colony-stimulating factor ; Megakaryocyte growth and development factor ; MGDF ; Myeloproliferative leukemia virus oncogene ligand
Categories	Elisa
Function	Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
Specificity	Natural and recombinant Mouse Thrombopoietin
Subcellular Location	Secreted
Detection Range	31.2-2000pg/ml
Entryname	TPO_MOUSE
Method Type	Sandwich
Platform	PF00758
Protein Name	Thrombopoietin
Sensitivity	15.83pg/mL
Sequence	50: MELTDLLLAA ; MLLAVARLTL ; SSPVAPACDP ; RLLNKLLRDS ; HLLHSRLSQC ; 100: PDVDPLSIPV ; LLPAVDFSLG ; EWKTQTEQSK ; AQDILGAVSL ; LLEGVMAARG ; 150: QLEPSCLSSL ; LGQLSGQVRL ; LLGALQGLLG ; TQLPLQGRTT ; AHKDPNALFL ; 200: SLQQLLRGKV ; RFLLLVEGPT ; LCVRRTLPTT ; AVPSSTSQLL ; TLNKFPNRTS ; 250: GLLETNFSVT ; ARTAGPGLLS ; RLQGFRVKIT ; PGQLNQTSRS ; PVQISGYLNR ; 300: THGPVNGTHG ; LFAGTSLQTL ; EASDISPGAF ; NKGSLAFNLQ ; GGLPPSPSLA ; 350: PDGHTPFPPS ; PALPTTHGSP ; PQLHPLFPDP ; STTMPNSTAP ; HPVTMYPHPR ; 356: NLSQET
Sequence Length	356
String	P40226

Uniprot	P40226
Gene Name	Thpo
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:21832
Unigene	Mm.3943

Reference	1. "Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo." Lok S., Kaushansky K., Holly R.D., Kuijper J.L., Lofton-Day C.E., Oort P.J., Grant F.J., Heipel M.D., Burkhead S.K., Kramer J.M., Bell L.A.N., Sprecher C.A., Blumberg H., Johnson R., Prunkard D., Ching A.F.T., Mathewes S.L., Bailey M.C., Forstrom J.W., Buddle M.M., Osborn S.G., Evans S.J., Sheppard P.O., Presnell S.R., O'Hara P.J., Hagen F.S., Roth G.J., Foster D.C.more... Nature369:565-568(1994) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1) tissue: Kidney. 2. "Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl." Bartley T.D., Bogenberger J., Hunt P., Li Y.-S., Lu H.S., Martin F., Chang M.-S., Samal B.B., Nichol J.L., Swift S., Johnson M.J., Hsu R.-Y., Parker V.P., Suggs S., Skrine J.D., Merewether L.A., Clogson C., Hsu E., Hokom M.M., Hornkohl A., Choi E., Pangelinan M., Sun Y., Mar V., McNich J., Simonet L., Jacobsen F., Xie C., Shutter J., Chute H., Basu R., Selander L., Trollinger D., Sieu L., Padilla D., Trail G., Elliott G., Izumi R., Covey T., Crouse J., Garcia A., Xu W., del Castillo J., Biron J., Cole S., Hu M.C.-T., Pacifici R., Ponting I., Saris C., Wen D., Yung Y.P., Lin H., Bosselman R.A.more... Cell77:1117-1124(1994) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1) tissue: Liver. 3. "Genomic structure, chromosomal localization, and conserved alternative splice forms of thrombopoietin." Gurney A.L., Kuang W.-J., Xie M.-H., Malloy B.E., Eaton D.L., de Sauvage F.J. Blood85:981-988(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2) 4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1) strain: FVB/N. tissue: Mammary gland. 5. "Diurnal expression of the thrombopoietin gene is regulated by CLOCK." Tracey C.J., Pan X., Catterson J.H., Harmar A.J., Hussain M.M., Hartley P.S. J. Thromb. Haemost.10:662-669(2012) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION

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SKU	Supplier No.	Size	Your price	Quantity
BHE13812005	E0135m	96T	$776		Add to Cart

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