Gp250 ; Low-density lipoprotein receptor relative with 11 ligand-binding repeats ; LDLR relative with 11 ligand-binding repeats ; SorLA-1 ; Sorting protein-related receptor containing LDLR class A repeats ; mSorLA
Categories
Elisa
Function
Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction. May play a role in neural organization, as well as the establishment of embryonic organ systems.
Specificity
Natural and recombinant Mouse Sortilin-related receptor