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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Serine/arginine-rich splicing factor 2

SKU : BHE13810921

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E11550m
Alternative Names	Protein PR264 ; Putative myelin regulatory factor 1 ; MRF-1 ; Splicing component ; 35 kDa ; Splicing factor SC35 ; SC-35 ; Splicing factor ; arginine/serine-rich 2 ; Pr264 ; Sfrs10 ; Sfrs2
Categories	Elisa
Function	Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA (By similarity). Can bind to the myelin basic protein (MBP) gene MB3 regulatory region and increase transcription of the mbp promoter in cells derived from the CNS.
Specificity	Natural and recombinant Mouse Serine/arginine-rich splicing factor 2
Subcellular Location	Nucleus
Detection Range	0.156-10ng/mL
Entryname	SRSF2_MOUSE
Method Type	Sandwich
Platform	PF00076
Protein Name	Serine/arginine-rich splicing factor 2
Sensitivity	0.091ng/mL
Sequence	50: MSYGRPPPDV ; EGMTSLKVDN ; LTYRTSPDTL ; RRVFEKYGRV ; GDVYIPRDRY ; 100: TKESRGFAFV ; RFHDKRDAED ; AMDAMDGAVL ; DGRELRVQMA ; RYGRPPDSHH ; 150: SRRGPPPRRY ; GGGGYGRRSR ; SPRRRRRSRS ; RSRSRSRSRS ; RSRYSRSKSR ; 200: SRTRSRSRST ; SKSRSARRSK ; SKSSSVSRSR ; SRSRSRSRSR ; SPPPVSKRES ; 221: KSRSRSKSPP ; KSPEEEGAVS ; S
Sequence Length	221
String	Q62093
Sub Unit	Interacts with CCNL1 and CCNL2. Interacts with SCAF11. Interacts with ZRSR2/U2AF1-RS2. Interacts with CCDC55 (via C-terminus) (By similarity). In vitro, self-associates and binds SRSF1/SFRS1 (ASF/SF2), SNRNP70 and U2AF1 but not U2AF2. Binds SREK1/SFRS12.

Uniprot	Q62093
Gene Name	Srsf2
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:20382
Unigene	Mm.21841

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810921	E11550m	96T	$776		Add to Cart

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