Neural-specific serine/arginine repetitive splicing factor of 100 kDa ; Neural-specific SR-related protein of 100 kDa
Categories
Elisa
Function
Splicing factor specifically required for neural cell differentiation. Acts in conjuction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts.
Specificity
Natural and recombinant Mouse Serine/arginine repetitive matrix protein 4