ELISA Kit for Mouse Ras-related protein Rap-1A

Mfr.No.	E3220m
Alternative Names	Ras-related protein Krev-1 ; Krev-1
Categories	Elisa
Function	Induces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner.
Specificity	Natural and recombinant Mouse Ras-related protein Rap-1A
Subcellular Location	Cell membrane Lipid-anchor
Detection Range	0.156-10ng/mL
Entryname	RAP1A_MOUSE
Method Type	Sandwich
Platform	PF00071
Protein Name	Ras-related protein Rap-1A
Sensitivity	0.078ng/mL
Sequence	50: MREYKLVVLG ; SGGVGKSALT ; VQFVQGIFVE ; KYDPTIEDSY ; RKQVEVDCQQ ; 100: CMLEILDTAG ; TEQFTAMRDL ; YMKNGQGFAL ; VYSITAQSTF ; NDLQDLREQI ; 150: LRVKDTEDVP ; MILVGNKCDL ; EDERVVGKEQ ; GQNLARQWCN ; CAFLESSAKS ; 184: KINVNEIFYD ; LVRQINRKTP ; VEKKKPKKKS ; CLLL
Sequence Length	184
String	P62835
Sub Unit	In its GTP-bound form interacts with PLCE1 and RADIL. Interacts with SGSM1, SGSM2 and SGSM3.

Reference	1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Czech II. tissue: Mammary tumor. 2. "Impaired vascular development in the yolk sac and allantois in mice lacking RA-GEF-1." Kanemura H., Satoh T., Bilasy S.E., Ueda S., Hirashima M., Kataoka T. Biochem. Biophys. Res. Commun.387:754-759(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION

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BHE13809877	E3220m	96T	$776		Add to Cart