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ELISA Kit for Mouse Poliovirus receptor-related protein 1

SKU : BHE13809222

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1711m
Alternative Names	Herpes virus entry mediator C ; Herpesvirus entry mediator C ; HveC ; Nectin-1 ; Hvec ; Prr1 ; CD111
Categories	Elisa
Function	Probably involved in cell adhesion. Receptor for alphaherpesvirus (HSV-1, HSV-2 and pseudorabies virus) entry into cells.
Specificity	Natural and recombinant Mouse Poliovirus receptor-related protein 1
Subcellular Location	Cell membrane Single-pass type I membrane protein
Detection Range	0.156-10ng/mL
Entryname	PVRL1_MOUSE
Method Type	Sandwich
Platform	PF08205
Protein Name	Poliovirus receptor-related protein 1
Sensitivity	0.085ng/mL
Sequence	50: MARMGLAGAA ; GRWWGLALGL ; TAFFLPGTHT ; QVVQVNDSMY ; GFIGTDVVLH ; 100: CSFANPLPSV ; KITQVTWQKA ; SNGSKQNMAI ; YNPTMGVSVL ; PPYEKRVEFL ; 150: RPSFIDGTIR ; LSGLELEDEG ; MYICEFATFP ; TGNRESQLNL ; TVMAKPTNWI ; 200: EGTRAVLRAR ; KGQDDKVLVA ; TCTSANGKPP ; SAVSWETRLK ; GEAEYQEIRN ; 250: PNGTVTVISR ; YRLVPSREAH ; RQSLACIVNY ; HLDRFRESLT ; LNVQYEPEVT ; 300: IEGFDGNWYL ; QRTDVKLTCK ; ADANPPATEY ; HWTTLNGSLP ; KGVEAQNRTL ; 350: FFRGPITYSL ; AGTYICEATN ; PIGTRSGQVE ; VNITEFPYTP ; TPEHGRRAGQ ; 400: MPTAIIGGVA ; GSVLLVLIVV ; GGIIVALRRR ; RHTFKGDYST ; KKHVYGNGYS ; 450: KAGIPQHHPP ; MAQNLQYPDD ; SDDEKKAGPL ; GGSSYEEEEE ; EEGGGGGERK ; 500: VGGPHPKYDE ; DAKRPYFTVD ; EAEARQDGYG ; DRTLGYQYDP ; EQLDLAENMV ; 515: SQNDGSFISK ; KEWYV
Sequence Length	515
String	Q9JKF6
Sub Unit	Can form trans-heterodimers with PVRL3/nectin-3. Interacts with HSV glycoprotein D (gD).

Uniprot	Q9JKF6
Gene Name	Pvrl1
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:58235
Unigene	Mm.335096

Reference	1. "The murine homolog of human nectin1 delta serves as a species nonspecific mediator for entry of human and animal alpha herpesviruses in a pathway independent of detectable binding to gD." Menotti L., Lopez M., Avitabile E., Stefan A., Cocchi F., Adelaide J., Lecocq E., Dubreuil P., Campadelli-Fiume G. Proc. Natl. Acad. Sci. U.S.A.97:4867-4872(2000) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "Striking similarity of murine nectin-1alpha to human nectin-1alpha (HveC) in sequence and activity as a glycoprotein D receptor for alphaherpesvirus entry." Shukla D., Dal Canto M.C., Rowe C.L., Spear P.G. J. Virol.74:11773-11781(2000) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 3. "Mouse nectin-1 (mPRR1), a herpesvirus receptor, is expressed in the floor plate during embryogenesis, suggesting a role in neural development." Zhan J., Wimmer E. Submitted (2000-08) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Swiss Webster. 4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: C57BL/6. tissue: Brain. 5. "Nectin-3: a new member of immunoglobulin-like cell adhesion molecules that shows homophilic and heterophilic cell-cell adhesion activities." Satoh-Horikawa K., Nakanishi H., Takahashi K., Miyahara M., Nishimura M., Tachibana K., Mizoguchi A., Takai Y. J. Biol. Chem.275:10291-10299(2000) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PVRL3 6. "Nectin: an adhesion molecule involved in formation of synapses." Mizoguchi A., Nakanishi H., Kimura K., Matsubara K., Ozaki-Kuroda K., Katata T., Honda T., Kiyohara Y., Heo K., Higashi M., Tsutsumi T., Sonoda S., Ide C., Takai Y. J. Cell Biol.156:555-565(2002) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT;SUBCELLULAR LOCATION 7. "Phosphoproteomic analysis of the developing mouse brain." Ballif B.A., Villen J., Beausoleil S.A., Schwartz D., Gygi S.P. Mol. Cell. Proteomics3:1093-1101(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS] tissue: Embryonic brain. 8. "Large-scale phosphorylation analysis of mouse liver." Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A.104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-433 AND SER-434;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS] tissue: Liver. 9. "The phagosomal proteome in interferon-gamma-activated macrophages." Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P. Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-421;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS] 10. "The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation." Gundry R.L., Raginski K., Tarasova Y., Tchernyshyov I., Bausch-Fluck D., Elliott S.T., Boheler K.R., Van Eyk J.E., Wollscheid B. Mol. Cell. Proteomics8:2555-2569(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-200; ASN-202; ASN-274 AND ASN-286 tissue: Myoblast. 11. "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins." Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M., Schiess R., Aebersold R., Watts J.D. Nat. Biotechnol.27:378-386(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-202; ASN-286 AND ASN-332 12. "Nectin-1 binds and signals through the fibroblast growth factor receptor." Bojesen K.B., Clausen O., Rohde K., Christensen C., Zhang L., Li S., Kohler L., Nielbo S., Nielsen J., Gjorlund M.D., Poulsen F.M., Bock E., Berezin V. J. Biol. Chem.287:37420-37433(2012) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STUCTURE BY NMR OF 241-334;FUNCTION;SUBUNIT;IG-LIKE DOMAIN;DISULFIDE BOND

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