The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Specificity
Natural and recombinant Mouse Muscarinic acetylcholine receptor M3
Subcellular Location
Cell membrane Multi-pass membrane protein Cell junction synapse postsynaptic cell membrane Multi-pass membrane protein Basolateral cell membrane Multi-pass membrane protein
"Isolation, sequence and functional expression of mouse muscarinic acetylcholine receptor genes." Gomeza J., Wess J. Submitted (2000-09) to the EMBL/GenBank/DDBJ databases
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