Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.
Specificity
Natural and recombinant Mouse Low-density lipoprotein receptor
Subcellular Location
Cell membrane Single-pass type I membrane protein Endomembrane system Single-pass type I membrane protein Membrane clathrin-coated pit Single-pass type I membrane protein