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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse DNA ligase 3

SKU : BHE13803830

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15016m
Alternative Names	DNA ligase III ; Polydeoxyribonucleotide synthase [ATP] 3
Categories	Elisa
Function	The alpha isoform interacts with DNA-repair protein XRCC1 and can correct defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. The beta isoform does not interact with XRCC1 and may be specifically involved in the completion of homologous recombination events that occur during meiotic prophase.
Specificity	Natural and recombinant Mouse DNA ligase 3
Subcellular Location	Nucleus
Detection Range	0.312-20ng/mL
Entryname	DNLI3_MOUSE
Method Type	Sandwich
Platform	PF04679
Protein Name	DNA ligase 3
Sensitivity	0.094ng/mL
Sequence	50: MTLAFKILFP ; RNLCALGRKE ; LCLFPEQNRW ; AAISQFSQWS ; ETNLLGGCCL ; 100: LQRRKPVLAL ; QRGHLRPRAT ; HLTFWPGSHV ; GLCTGPCAMA ; EQRFCVDYAK ; 150: RGTAGCKKCK ; EKIVKGVCRI ; GKVVPNPFSE ; SGGDMKEWYH ; IKCMFEKLER ; 200: ARATTKKIED ; LTELEGWEEL ; EDNEKEQISQ ; HIADLSSKAA ; ATPKKKAAVQ ; 250: AKLTTTGQVT ; SPVKGASFIT ; STNPRKFSGF ; SAAKPNNSEQ ; APSSPAPGTS ; 300: LSASKCDPKH ; KDCLLREFRK ; LCAMVAENPS ; YNTKTQIIHD ; FLQKGSTGGF ; 350: SDGFHGDVYL ; TVKLLLPGVI ; KSVYNLNDKQ ; IVKLFSRIFN ; CNPDDMARDL ; 400: EQGDVSETIR ; IFFEQSKSFP ; PAAKSLLTIQ ; EVDAFLLHLS ; KLTKEDEQQQ ; 450: ALQDIASRCT ; ANDLKCIIRL ; IKHDLKMNSG ; AKHVLDALDP ; NAYEAFKASR ; 500: NLQDVVERVL ; HNEQEVEKDP ; GRRRALRVQA ; SLMTPVQPML ; AEACKSIEYA ; 550: MKKCPNGMFS ; EIKYDGERVQ ; VHKKGDHFSY ; FSRSLKPVLP ; HKVAHFKDYI ; 600: PKAFPGGQSM ; ILDSEVLLID ; NNTGKPLPFG ; TLGVHKKAAF ; QDANVCLFVF ; 650: DCIYFNDVSL ; MDRPLCERRK ; FLHDNMVEIR ; NRIMFSEMKQ ; VTKASDLADM ; 700: INRVIREGLE ; GLVLKDVKGT ; YEPGKRHWLK ; VKKDYLNEGA ; MADTADLVVL ; 750: GAFYGQGSKG ; GMMSIFLMGC ; YDPDSQKWCT ; VTKCAGGHDD ; ATLARLQKEL ; 800: VMVKISKDPS ; KIPSWLKINK ; IYYPDFIVPD ; PKKAAVWEIT ; GAEFSRSEAH ; 850: TADGISIRFP ; RCTRIRDDKD ; WKSATNLPQL ; KELYQLSKDK ; ADFAVVAGDE ; 900: ASPTTGGSSG ; ENEGTAGSAG ; PCKGPPSKSS ; ASAKTTEQKL ; NSPSSRGGIK ; 950: PIPKHSPMKP ; GEKLAVKSSP ; VKVGMKRKAT ; DETPCLKKVL ; LDVFTGVRLY ; 1000: LPPSTPDFKR ; LKRYFVAFDG ; DLVQEFDMGS ; ATHVLGNREK ; NTDAQLVSSE ; 1015: WIWACIRKRR ; LIAPC
Sequence Length	1015
String	P97386

Uniprot	P97386
Gene Name	Lig3
Immunogen Species	Mus musculus (Mouse)
Unigene	Mm.277136

Reference	1. "An alternative splicing event which occurs in mouse pachytene spermatocytes generates a form of DNA ligase III with distinct biochemical properties that may function in meiotic recombination." Mackey Z.B., Ramos W., Levin D.S., Walter C.A., McCarrey J.R., Tomkinson A.E. Mol. Cell. Biol.17:989-998(1997) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS ALPHA AND BETA) tissue: Testis. 2. "Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.more... PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] strain: C57BL/6J. 3. "Large-scale phosphorylation analysis of mouse liver." Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A.104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-211;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS] tissue: Liver. 4. "The phagosomal proteome in interferon-gamma-activated macrophages." Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P. Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-211;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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SKU	Supplier No.	Size	Your price	Quantity
BHE13803830	E15016m	96T	$776		Add to Cart

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