JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
orders@biohippo.com

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse B-cell lymphoma 6 protein homolog

SKU : BHE13801651

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E11123m
Alternative Names	Bcl-6
Categories	Elisa
Function	Transcriptional repressor which is required for germinal center formation and antibody affinity maturation. Probably plays an important role in lymphomagenesis.
Specificity	Natural and recombinant Mouse B-cell lymphoma 6 protein homolog
Subcellular Location	Nucleus
Entryname	BCL6_MOUSE
Platform	PF00651
Protein Name	B-cell lymphoma 6 protein homolog
Sequence	50: MASPADSCIQ ; FTRHASDVLL ; NLNRLRSRDI ; LTDVVIVVSR ; EQFRAHKTVL ; 100: MACSGLFYSI ; FTDQLKCNLS ; VINLDPEISP ; EGFCILLDFM ; YTSRLNLREG ; 150: NIMAVMTTAM ; YLQMEHVVDT ; CRKFIKASEA ; EMAPALKPPR ; EEFLNSRMLM ; 200: PHDIMAYRGR ; EVVENNMPLR ; NTPGCESRAF ; APPLYSGLST ; PPASYPMYSH ; 250: LPLSTFLFSD ; EELRDAPRMP ; VANPFPKERA ; LPCDSARQVP ; NEYSRPAMEV ; 300: SPSLCHSNIY ; SPKEAVPEEA ; RSDIHYSVPE ; GPKPAVPSAR ; NAPYFPCDKA ; 350: SKEEERPSSE ; DEIALHFEPP ; NAPLNRKGLV ; SPQSPQKSDC ; QPNSPTESCS ; 400: SKNACILQAS ; GSPPAKSPTD ; PKACNWKKYK ; FIVLNSLNQN ; AKPEGSEQAE ; 450: LGRLSPRAYP ; APPACQPPME ; PANLDLQSPT ; KLSASGEDST ; IPQASRLNNL ; 500: VNRSLAGSPR ; SSSESHSPLY ; MHPPKCTSCG ; SQSPQHTEMC ; LHTAGPTFPE ; 550: EMGETQSEYS ; DSSCENGTFF ; CNECDCRFSE ; EASLKRHTLQ ; THSDKPYKCD ; 600: RCQASFRYKG ; NLASHKTVHT ; GEKPYRCNIC ; GAQFNRPANL ; KTHTRIHSGE ; 650: KPYKCETCGA ; RFVQVAHLRA ; HVLIHTGEKP ; YPCEICGTRF ; RHLQTLKSHL ; 700: RIHTGEKPYH ; CEKCNLHFRH ; KSQLRLHLRQ ; KHGAITNTKV ; QYRVSAADLP ; 707: PELPKAC
Sequence Length	707
String	P41183
Sub Unit	Homodimer. Interacts (via BTB domain) with BCOR; the interaction is direct. Interacts (via BTB domain) with NCOR2; the interaction is direct. Interacts with ZBTB7 and BCL6B. Interacts with the catalytic domain of HDAC9.

Uniprot	P41183
Gene Name	Bcl6
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:12053
Unigene	Mm.347398

Reference	1. "The murine BCL6 gene is induced in activated lymphocytes as an immediate early gene." Fukuda T., Miki T., Yoshida T., Hatano M., Ohashi K., Hirosawa S., Tokuhisa T. Oncogene11:1657-1663(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: BALB/c. tissue: Skeletal muscle. 2. "BCL-6 expression during B-cell activation." Allman D., Jain A., Dent A., Maile R.R., Selvaggi T., Kehry M.R., Staudt L.M. Blood87:5257-5268(1996) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Muscle. 3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Olfactory epithelium. 4. "BAZF, a novel Bcl6 homolog, functions as a transcriptional repressor." Okabe S., Fukuda T., Ishibashi K., Kojima S., Okada S., Hatano M., Ebara M., Saisho H., Tokuhisa T. Mol. Cell. Biol.18:4235-4244(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BCL6B 5. "Novel BTB/POZ domain zinc-finger protein, LRF, is a potential target of the LAZ-3/BCL-6 oncogene." Davies J.M., Hawe N., Kabarowski J., Huang Q.-H., Zhu J., Brand N.J., Leprince D., Dhordain P., Cook M., Moriss-Kay G., Zelent A. Oncogene18:365-375(1999) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ZBTB7;SUBCELLULAR LOCATION 6. "BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control." Shaffer A.L., Yu X., He Y., Boldrick J., Chan E.P., Staudt L.M. Immunity13:199-212(2000) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS TRANSCRIPTIONAL REPRESSOR;DISRUPTION PHENOTYPE 7. "Role for Bcl-6 in the generation and maintenance of memory CD8+ T-cells." Ichii H., Sakamoto A., Hatano M., Okada S., Toyama H., Taki S., Arima M., Kuroda Y., Tokuhisa T. Nat. Immunol.3:558-563(2002) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN MEMORY CD8(+) T-CELL MAINTENANCE;DISRUPTION PHENOTYPE 8. "Genotoxic stress regulates expression of the proto-oncogene Bcl6 in germinal center B cells." Phan R.T., Saito M., Kitagawa Y., Means A.R., Dalla-Favera R. Nat. Immunol.8:1132-1139(2007) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY 9. "BCL6 positively regulates AID and germinal center gene expression via repression of miR-155." Basso K., Schneider C., Shen Q., Holmes A.B., Setty M., Leslie C., Dalla-Favera R. J. Exp. Med.209:2455-2465(2012) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN MIRNA REGULATION;TISSUE SPECIFICITY 10. "BCL6 controls neurogenesis through Sirt1-dependent epigenetic repression of selective Notch targets." Tiberi L., van den Ameele J., Dimidschstein J., Piccirilli J., Gall D., Herpoel A., Bilheu A., Bonnefont J., Iacovino M., Kyba M., Bouschet T., Vanderhaeghen P. Nat. Neurosci.15:1627-1635(2012) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN NEUROGENESIS;INTERACTION WITH NOTCH1 AND SIRT1;DEVELOPMENTAL STAGE;DISRUPTION PHENOTYPE 11. "A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters." Hatzi K., Jiang Y., Huang C., Garrett-Bakelman F., Gearhart M.D., Giannopoulou E.G., Zumbo P., Kirouac K., Bhaskara S., Polo J.M., Kormaksson M., Mackerell A.D. Jr., Xue F., Mason C.E., Hiebert S.W., Prive G.G., Cerchietti L., Bardwell V.J., Elemento O., Melnick A.more... Cell Rep.4:578-588(2013) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF ASN-21 AND HIS-116 12. "Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanisms." Huang C., Hatzi K., Melnick A. Nat. Immunol.14:380-388(2013) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN GERMINAL CENTER REACTIONS;DNA-BINDING;DOMAIN;INTERACTION WITH SMRT;DISRUPTION PHENOTYPE;MUTAGENESIS OF ASN-21; HIS-116; 377-LYS--LYS-380 AND 577-CYS--CYS-580

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13801651	E11123m	96T	$776		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.