Interferon-induced 15 kDa protein ; Interferon-induced 17 kDa protein ; IP17 ; Ubiquitin cross-reactive protein ; hUCRP ; G1P2 ; UCRP
Categories
Elisa
Function
In response to IFN-tau secreted by the conceptus, may ligate to and regulate proteins involved in the release of prostaglandin F2-alpha (PGF), and thus prevent lysis of the corpus luteum and maintain the pregnancy.
Specificity
Natural and recombinant Human Ubiquitin-like protein ISG15
Subcellular Location
Cytoplasm Secreted UCRP conjugates seem to be noncovalently associated with the intermediate filaments and distributed in a punctate patte. Also secreted.
Interacts with, and is conjugated to its targets by the UBE1L (E1 enzyme) and UBE2E2 (E2 enzyme) (Probable). Interaction with influenza B NS1 protein inhibits this conjugation.