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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Thioredoxin-interacting protein

SKU : BHE13811677

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1162h
Alternative Names	Thioredoxin-binding protein 2 ; Vitamin D3 up-regulated protein 1 ; VDUP1
Categories	Elisa
Function	May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth.
Specificity	Natural and recombinant Human Thioredoxin-interacting protein
Subcellular Location	Cytoplasm
Detection Range	0.156-10ng/mL
Entryname	TXNIP_HUMAN
Method Type	Sandwich
Platform	PF02752
Protein Name	Thioredoxin-interacting protein
Sensitivity	0.039ng/mL
Sequence	50: MVMFKKIKSF ; EVVFNDPEKV ; YGSGEKVAGR ; VIVEVCEVTR ; VKAVRILACG ; 100: VAKVLWMQGS ; QQCKQTSEYL ; RYEDTLLLED ; QPTGENEMVI ; MRPGNKYEYK ; 150: FGFELPQGPL ; GTSFKGKYGC ; VDYWVKAFLD ; RPSQPTQETK ; KNFEVVDLVD ; 200: VNTPDLMAPV ; SAKKEKKVSC ; MFIPDGRVSV ; SARIDRKGFC ; EGDEISIHAD ; 250: FENTCSRIVV ; PKAAIVARHT ; YLANGQTKVL ; TQKLSSVRGN ; HIISGTCASW ; 300: RGKSLRVQKI ; RPSILGCNIL ; RVEYSLLIYV ; SVPGSKKVIL ; DLPLVIGSRS ; 350: GLSSRTSSMA ; SRTSSEMSWV ; DLNIPDTPEA ; PPCYMDVIPE ; DHRLESPTTP ; 391: LLDDMDGSQD ; SPIFMYAPEF ; KFMPPPTYTE ; VDPCILNNNV ; Q
Sequence Length	391
String	Q9H3M7
Sub Unit	Interacts with TXN/thioredoxin through its redox-active site. Interacts with transcriptional repressors ZBTB16, ZBTB32 and HDAC1. Interacts (via C-terminus) with ITCH (via WW domains).

Uniprot	Q9H3M7
Gene Name	TXNIP
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:10628
Unigene	Hs.533977

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811677	E1162h	96T	$736		Add to Cart

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