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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Sodium channel protein type 8 subunit alpha

SKU : BHE13810363

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15346h
Alternative Names	Sodium channel protein type VIII subunit alpha ; Voltage-gated sodium channel subunit alpha Nav1.6 ; MED
Categories	Elisa
Function	Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation.
Specificity	Natural and recombinant Human Sodium channel protein type 8 subunit alpha
Subcellular Location	Isoform 5 Cytoplasmic vesicle Some vesicles are localized adjacent to melanoma invadopodia and macrophage podosomes. Does not localize to the plasma membrane.
Detection Range	0.156-10ng/mL
Entryname	SCN8A_HUMAN
Method Type	Sandwich
Platform	PF11933
Protein Name	Sodium channel protein type 8 subunit alpha
Sensitivity	0.056ng/mL
Sequence	50: MAARLLAPPG ; PDSFKPFTPE ; SLANIERRIA ; ESKLKKPPKA ; DGSHREDDED ; 100: SKPKPNSDLE ; AGKSLPFIYG ; DIPQGLVAVP ; LEDFDPYYLT ; QKTFVVLNRG ; 150: KTLFRFSATP ; ALYILSPFNL ; IRRIAIKILI ; HSVFSMIIMC ; TILTNCVFMT ; 200: FSNPPDWSKN ; VEYTFTGIYT ; FESLVKIIAR ; GFCIDGFTFL ; RDPWNWLDFS ; 250: VIMMAYITEF ; VNLGNVSALR ; TFRVLRALKT ; ISVIPGLKTI ; VGALIQSVKK ; 300: LSDVMILTVF ; CLSVFALIGL ; QLFMGNLRNK ; CVVWPINFNE ; SYLENGTKGF ; 350: DWEEYINNKT ; NFYTVPGMLE ; PLLCGNSSDA ; GQCPEGYQCM ; KAGRNPNYGY ; 400: TSFDTFSWAF ; LALFRLMTQD ; YWENLYQLTL ; RAAGKTYMIF ; FVLVIFVGSF ; 450: YLVNLILAVV ; AMAYEEQNQA ; TLEEAEQKEA ; EFKAMLEQLK ; KQQEEAQAAA ; 500: MATSAGTVSE ; DAIEEEGEEG ; GGSPRSSSEI ; SKLSSKSAKE ; RRNRRKKRKQ ; 550: KELSEGEEKG ; DPEKVFKSES ; EDGMRRKAFR ; LPDNRIGRKF ; SIMNQSLLSI ; 600: PGSPFLSRHN ; SKSSIFSFRG ; PGRFRDPGSE ; NEFADDEHST ; VEESEGRRDS ; 650: LFIPIRARER ; RSSYSGYSGY ; SQGSRSSRIF ; PSLRRSVKRN ; STVDCNGVVS ; 700: LIGGPGSHIG ; GRLLPEATTE ; VEIKKKGPGS ; LLVSMDQLAS ; YGRKDRINSI ; 750: MSVVTNTLVE ; ELEESQRKCP ; PCWYKFANTF ; LIWECHPYWI ; KLKEIVNLIV ; 800: MDPFVDLAIT ; ICIVLNTLFM ; AMEHHPMTPQ ; FEHVLAVGNL ; VFTGIFTAEM ; 850: FLKLIAMDPY ; YYFQEGWNIF ; DGFIVSLSLM ; ELSLADVEGL ; SVLRSFRLLR ; 900: VFKLAKSWPT ; LNMLIKIIGN ; SVGALGNLTL ; VLAIIVFIFA ; VVGMQLFGKS ; 950: YKECVCKINQ ; DCELPRWHMH ; DFFHSFLIVF ; RVLCGEWIET ; MWDCMEVAGQ ; 1000: AMCLIVFMMV ; MVIGNLVVLN ; LFLALLLSSF ; SADNLAATDD ; DGEMNNLQIS ; 1050: VIRIKKGVAW ; TKLKVHAFMQ ; AHFKQREADE ; VKPLDELYEK ; KANCIANHTG ; 1100: ADIHRNGDFQ ; KNGNGTTSGI ; GSSVEKYIID ; EDHMSFINNP ; NLTVRVPIAV ; 1150: GESDFENLNT ; EDVSSESDPE ; GSKDKLDDTS ; SSEGSTIDIK ; PEVEEVPVEQ ; 1200: PEEYLDPDAC ; FTEGCVQRFK ; CCQVNIEEGL ; GKSWWILRKT ; CFLIVEHNWF ; 1250: ETFIIFMILL ; SSGALAFEDI ; YIEQRKTIRT ; ILEYADKVFT ; YIFILEMLLK ; 1300: WTAYGFVKFF ; TNAWCWLDFL ; IVAVSLVSLI ; ANALGYSELG ; AIKSLRTLRA ; 1350: LRPLRALSRF ; EGMRVVVNAL ; VGAIPSIMNV ; LLVCLIFWLI ; FSIMGVNLFA ; 1400: GKYHYCFNET ; SEIRFEIEDV ; NNKTECEKLM ; EGNNTEIRWK ; NVKINFDNVG ; 1450: AGYLALLQVA ; TFKGWMDIMY ; AAVDSRKPDE ; QPKYEDNIYM ; YIYFVIFIIF ; 1500: GSFFTLNLFI ; GVIIDNFNQQ ; KKKFGGQDIF ; MTEEQKKYYN ; AMKKLGSKKP ; 1550: QKPIPRPLNK ; IQGIVFDFVT ; QQAFDIVIMM ; LICLNMVTMM ; VETDTQSKQM ; 1600: ENILYWINLV ; FVIFFTCECV ; LKMFALRHYY ; FTIGWNIFDF ; VVVILSIVGM ; 1650: FLADIIEKYF ; VSPTLFRVIR ; LARIGRILRL ; IKGAKGIRTL ; LFALMMSLPA ; 1700: LFNIGLLLFL ; VMFIFSIFGM ; SNFAYVKHEA ; GIDDMFNFET ; FGNSMICLFQ ; 1750: ITTSAGWDGL ; LLPILNRPPD ; CSLDKEHPGS ; GFKGDCGNPS ; VGIFFFVSYI ; 1800: IISFLIVVNM ; YIAIILENFS ; VATEESADPL ; SEDDFETFYE ; IWEKFDPDAT ; 1850: QFIEYCKLAD ; FADALEHPLR ; VPKPNTIELI ; AMDLPMVSGD ; RIHCLDILFA ; 1900: FTKRVLGDSG ; ELDILRQQME ; ERFVASNPSK ; VSYEPITTTL ; RRKQEEVSAV ; 1950: VLQRAYRGHL ; ARRGFICKKT ; TSNKLENGGT ; HREKKESTPS ; TASLPSYDSV ; 1980: TKPEKEKQQR ; AEEGRRERAK ; RQKEVRESKC ;
Sequence Length	1980
String	Q9UQD0
Sub Unit	Interacts with NEDD4 and NEDD4L.

Uniprot	Q9UQD0
Gene Name	SCN8A
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:6334
Unigene	Hs.436550

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810363	E15346h	96T	$736		Add to Cart

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