ELISA Kit for Human Signaling lymphocytic activation molecule

Mfr.No.	E9273h
Alternative Names	CDw150 ; IPO-3 ; SLAM family member 1 ; CD150 ; SLAM
Categories	Elisa
Function	High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
Specificity	Natural and recombinant Human Signaling lymphocytic activation molecule
Subcellular Location	Cell membrane Single-pass type I membrane protein Present on the surface of B-cells and T-cells.
Entryname	SLAF1_HUMAN
Platform	PF06214
Protein Name	Signaling lymphocytic activation molecule
Sequence	50: MDPKGLLSLT ; FVLFLSLAFG ; ASYGTGGRMM ; NCPKILRQLG ; SKVLLPLTYE ; 100: RINKSMNKSI ; HIVVTMAKSL ; ENSVENKIVS ; LDPSEAGPPR ; YLGDRYKFYL ; 150: ENLTLGIRES ; RKEDEGWYLM ; TLEKNVSVQR ; FCLQLRLYEQ ; VSTPEIKVLN ; 200: KTQENGTCTL ; ILGCTVEKGD ; HVAYSWSEKA ; GTHPLNPANS ; SHLLSLTLGP ; 250: QHADNIYICT ; VSNPISNNSQ ; TFSPWPGCRT ; DPSETKPWAV ; YAGLLGGVIM ; 300: ILIMVVILQL ; RRRGKTNHYQ ; TTVEKKSLTI ; YAQVQKPGPL ; QKKLDSFPAQ ; 335: DPCTTIYVAA ; TEPVPESVQE ; TNSITVYASV ; TLPES
Sequence Length	335
String	Q13291
Sub Unit	Interacts (via cytoplasmic domain) with SH2D1A, and with PTPN11. Interacts with INPP5D/SHIP1. Binds to Measles virus H protein and acts as a receptor for this virus.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810260	E9273h	96T	$736		Add to Cart