Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Specificity
Natural and recombinant Human Programmed cell death 1 ligand 2
Subcellular Location
Isoform 1 Cell membrane Single-pass type I membrane protein