Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid tuover as well as in protection against oxidative injury.
Specificity
Natural and recombinant Human Peroxiredoxin-6
Subcellular Location
Cytoplasm Lysosome Cytoplasmic vesicle Also found in lung secretory organelles.
Homotetramer. Interacts with GSTP1; mediates PRDX6 glutathionylation and regeneration. May interact with HTR2A (By similarity). Interacts with APEX1 and STH.