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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Metastasis-suppressor KiSS-1

SKU : BHE13806717

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E2063h
Alternative Names	Kisspeptin-1 ; PP5098
Categories	Elisa
Function	Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-10 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophoblast. Kp-10, but not other kisspeptins, increased intracellular Ca(2+) levels in isolated first trimester trophoblasts. Kp-10 is a paracrine/endocrine regulator in fine-tuning trophoblast invasion generated by the trophoblast itself. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.
Specificity	Natural and recombinant Human Metastasis-suppressor KiSS-1
Subcellular Location	Secreted
Detection Range	0.156-10ng/mL
Entryname	KISS1_HUMAN
Method Type	Sandwich
Protein Name	Metastasis-suppressor KiSS-1
Sensitivity	0.078ng/mL
Sequence	50: MNSLVSWQLL ; LFLCATHFGE ; PLEKVASVGN ; SRPTGQQLES ; LGLLAPGEQS ; 100: LPCTERKPAA ; TARLSRRGTS ; LSPPPESSGS ; PQQPGLSAPH ; SRQIPAPQGA ; 138: VLVQREKDLP ; NYNWNSFGLR ; FGKREAAPGN ; HGRSAGRG
Sequence Length	138
String	Q15726

Uniprot	Q15726
Gene Name	KISS1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:3814
Unigene	Hs.95008

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806717	E2063h	96T	$736		Add to Cart

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