JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
orders@biohippo.com

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Human Major prion protein

SKU : BHE13809186

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E9345h
Alternative Names	ASCR ; PrP27-30 ; PrP33-35C ; CD230 ; ALTPRP ; PRIP ; PRP
Categories	Elisa
Function	The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).
Specificity	Natural and recombinant Human Major prion protein
Subcellular Location	Isoform 2 Cytoplasm Nucleus Accumulates outside the secretory route in the cytoplasm, from where it relocates to the nucleus.
Detection Range	0.312-20ng/mL
Entryname	PRIO_HUMAN
Method Type	Sandwich
Platform	PF00377
Protein Name	Major prion protein
Sensitivity	0.19ng/mL
Sequence	50: MANLGCWMLV ; LFVATWSDLG ; LCKKRPKPGG ; WNTGGSRYPG ; QGSPGGNRYP ; 100: PQGGGGWGQP ; HGGGWGQPHG ; GGWGQPHGGG ; WGQPHGGGWG ; QGGGTHSQWN ; 150: KPSKPKTNMK ; HMAGAAAAGA ; VVGGLGGYML ; GSAMSRPIIH ; FGSDYEDRYY ; 200: RENMHRYPNQ ; VYYRPMDEYS ; NQNNFVHDCV ; NITIKQHTVT ; TTTKGENFTE ; 250: TDVKMMERVV ; EQMCITQYER ; ESQAYYQRGS ; SMVLFSSPPV ; ILLISFLIFL ; 253: IVG
Sequence Length	253
String	P04156
Sub Unit	Monomer and homodimer. Has a tendency to aggregate into amyloid fibrils containing a cross-beta spine, formed by a steric zipper of superposed beta-strands. Soluble oligomers may represent an intermediate stage on the path to fibril formation. Copper binding may promote oligomerization. Interacts with GRB2, APP, ERI3/PRNPIP and SYN1. Mislocalized cytosolically exposed PrP interacts with MGRN1; this interaction alters MGRN1 subcellular location and causes lysosomal enlargement.

Uniprot	P04156
Gene Name	PRNP
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:5621
Unigene	Hs.472010

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13809186	E9345h	96T	$736		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.