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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Heat shock factor protein 1

SKU : BHE13805985

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0435h
Alternative Names	Heat shock transcription factor 1 ; HSTF 1 ; HSTF1
Categories	Elisa
Function	DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.
Specificity	Natural and recombinant Human Heat shock factor protein 1
Subcellular Location	Cytoplasm Nucleus Cytoplasmic during normal growth. On activation, translocates to nuclear stress granules. Colocalizes with SUMO1 in nuclear stress granules.
Detection Range	0.312-20ng/mL
Entryname	HSF1_HUMAN
Method Type	Sandwich
Platform	PF00447
Protein Name	Heat shock factor protein 1
Sensitivity	0.11ng/mL
Sequence	50: MDLPVGPGAA ; GPSNVPAFLT ; KLWTLVSDPD ; TDALICWSPS ; GNSFHVFDQG ; 100: QFAKEVLPKY ; FKHNNMASFV ; RQLNMYGFRK ; VVHIEQGGLV ; KPERDDTEFQ ; 150: HPCFLRGQEQ ; LLENIKRKVT ; SVSTLKSEDI ; KIRQDSVTKL ; LTDVQLMKGK ; 200: QECMDSKLLA ; MKHENEALWR ; EVASLRQKHA ; QQQKVVNKLI ; QFLISLVQSN ; 250: RILGVKRKIP ; LMLNDSGSAH ; SMPKYSRQFS ; LEHVHGSGPY ; SAPSPAYSSS ; 300: SLYAPDAVAS ; SGPIISDITE ; LAPASPMASP ; GGSIDERPLS ; SSPLVRVKEE ; 350: PPSPPQSPRV ; EEASPGRPSS ; VDTLLSPTAL ; IDSILRESEP ; APASVTALTD ; 400: ARGHTDTEGR ; PPSPPPTSTP ; EKCLSVACLD ; KNELSDHLDA ; MDSNLDNLQT ; 450: MLSSHGFSVD ; TSALLDLFSP ; SVTVPDMSLP ; DLDSSLASIQ ; ELLSPQEPPR ; 500: PPEAENSSPD ; SGKQLVHYTA ; QPLFLLDPGS ; VDTGSNDLPV ; LFELGEGSYF ; 529: SEGDGFAEDP ; TISLLTGSEP ; PKAKDPTVS
Sequence Length	529
String	Q00613
Sub Unit	Monomer. Under normal conditions, interacts with HSP90AA1 in the HSP90 multichaperone complex; the interaction prevents trimerization and activation of HSF1. On activation by heat-stress or by other factors such as metal ions, HSF1 is released from the complex, homotrimerizes, is hyperphosphorylated and translocated to the nucleus where, subsequently, it can activate transcription. Binds the complex through the regulatory domain. Interacts with SYMPK and CSTF2 in heat-stressed cells. Interacts with FKBP4 in the HSP90 multichaperone complex; the interaction is independent of the phosphorylation state of HSF1. Interacts with MAPKAPK2.

Uniprot	Q00613
Gene Name	HSF1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:3297
Unigene	Hs.530227

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805985	E0435h	96T	$736		Add to Cart

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