ELISA Kit for Human Gremlin-1

Mfr.No.	E2130h
Alternative Names	Cell proliferation-inducing gene 2 protein ; Cysteine knot superfamily 1 ; BMP antagonist 1 ; DAN domain family member 2 ; Down-regulated in Mos-transformed cells protein ; Increased in high glucose protein 2 ; IHG-2 ; CKTSF1B1 ; DAND2 ; DRM ; PIG2
Categories	Elisa
Function	Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patteing in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Acts as inhibitor of monocyte chemotaxis.
Specificity	Natural and recombinant Human Gremlin-1
Subcellular Location	Secreted
Detection Range	0.125-8ng/mL
Entryname	GREM1_HUMAN
Method Type	Sandwich
Platform	PF03045
Protein Name	Gremlin-1
Sensitivity	0.032ng/mL
Sequence	50: MSRTAYTVGA ; LLLLLGTLLP ; AAEGKKKGSQ ; GAIPPPDKAQ ; HNDSEQTQSP ; 100: QQPGSRNRGR ; GQGRGTAMPG ; EEVLESSQEA ; LHVTERKYLK ; RDWCKTQPLK ; 150: QTIHEEGCNS ; RTIINRFCYG ; QCNSFYIPRH ; IRKEEGSFQS ; CSFCKPKKFT ; 184: TMMVTLNCPE ; LQPPTKKKRV ; TRVKQCRCIS ; IDLD
Sequence Length	184
String	O60565
Sub Unit	Interacts with SLIT1 and SLIT2 in a glycosylation-dependent manner.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805524	E2130h	96T	$736		Add to Cart