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ELISA Kit for Human Glutamate decarboxylase 2

BHE13803499
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+1 866.986.9598
Email
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Uniprot Q05329
Gene Name GAD2
Immunogen Species Homo Sapiens (Human)
Kegg hsa:2572
Unigene Hs.231829
Reference
  1. 1.
    "Cloning and primary structure of a human islet isoform of glutamic acid decarboxylase from chromosome 10."
    Karlsen A.E., Hagopian W.A., Grubin C.E., Dube S., Disteche C.M., Adler D.A., Barmeier H., Mathewes S., Grant F.J., Foster D., Lemark A.
    Proc. Natl. Acad. Sci. U.S.A.88:8337-8341(1991) [PubMed] [Europe PMC] [Abstract]
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    tissue: Pancreatic islet.
  2. 2.
    "Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single gene."
    Bu D.-F., Erlander M.G., Hitz B.C., Tillakaratne N.J., Kaufman D.L., Wagner-Mcpherson C.B., Evans G.A., Tobin A.J.
    Proc. Natl. Acad. Sci. U.S.A.89:2115-2119(1992) [PubMed] [Europe PMC] [Abstract]
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
  3. 3.
    "The exon-intron organization of the genes (GAD1 and GAD2) encoding two human glutamate decarboxylases (GAD67 and GAD65) suggests that they derive from a common ancestral GAD."
    Bu D.-F., Tobin A.J.
    Genomics21:222-228(1994) [PubMed] [Europe PMC] [Abstract]
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
  4. 4.
    NIEHS SNPs program
    Submitted (2003-07) to the EMBL/GenBank/DDBJ databases
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS ARG-12; ASN-124; ARG-286 AND GLN-375
  5. 5.
    "Characterization of a linear epitope within the human pancreatic 64-kDa glutamic acid decarboxylase and its autoimmune recognition by sera from insulin-dependent diabetes mellitus patients."
    Mauch L., Abney C.C., Berg H., Scherbaum W.A., Liedvogel B., Northemann W.
    Eur. J. Biochem.212:597-603(1993) [PubMed] [Europe PMC] [Abstract]
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 6-585
    tissue: Pancreas.
  6. 6.
    "Differential expression of GAD65 and GAD67 in human, rat, and mouse pancreatic islets."
    Kim J., Richter W., Aanstoot H.-J., Shi Y., Fu Q., Rajotte R., Waock G., Baekkeskov S.
    Diabetes42:1799-1808(1993) [PubMed] [Europe PMC] [Abstract]
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 245-585
  7. 7.
    "Phosphorylation of serine residues 3, 6, 10, and 13 distinguishes membrane anchored from soluble glutamic acid decarboxylase 65 and is restricted to glutamic acid decarboxylase 65alpha."
    Namchuk M., Lindsay L., Turck C.W., Kanaani J., Baekkeskov S.
    J. Biol. Chem.272:1548-1557(1997) [PubMed] [Europe PMC] [Abstract]
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-3; SER-6; SER-10 AND SER-13;BIOPHYSICOCHEMICAL PROPERTIES
  8. 8.
    "A combination of three distinct trafficking signals mediates axonal targeting and presynaptic clustering of GAD65."
    Kanaani J., El-Din El-Husseini A., Aguilera-Moreno A., Diacovo J.M., Bredt D.S., Baekkeskov S.
    J. Cell Biol.158:1229-1238(2002) [PubMed] [Europe PMC] [Abstract]
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;PALMITOYLATION AT CYS-30 AND CYS-45
  9. 9.
    "A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes."
    Corper A.L., Stratmann T., Apostolopoulos V., Scott C.A., Garcia K.C., Kang A.S., Wilson I.A., Teyton L.
    Science288:505-511(2000) [PubMed] [Europe PMC] [Abstract]
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF 222-235 IN COMPLEX WITH MHC
  10. 10.
    [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 88-584 IN COMPLEX WITH SUBSTRATE;SUBUNIT;COFACTOR
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