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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Follistatin-related protein 3

SKU : BHE13812138

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0127h
Alternative Names	Follistatin-like protein 3 ; Follistatin-related gene protein ; FLRG ; UNQ674/PRO1308
Categories	Elisa
Function	Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiationc. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. Isoform 2 or the nuclear form is probably involved in transcriptional regulation via interaction with MLLT10.
Specificity	Natural and recombinant Human Follistatin-related protein 3
Subcellular Location	Isoform 2 Nucleus Although alteative initiation has been demonstrated and resulted in different localization, the major source of nuclear FSTL3 appears not to depend on translation initation at Met-27 according to.
Detection Range	0.312-20ng/mL
Entryname	FSTL3_HUMAN
Method Type	Sandwich
Platform	PF09289
Protein Name	Follistatin-related protein 3
Sensitivity	0.11ng/mL
Sequence	50: MRPGAPGPLW ; PLPWGALAWA ; VGFVSSMGSG ; NPAPGGVCWL ; QQGQEATCSL ; 100: VLQTDVTRAE ; CCASGNIDTA ; WSNLTHPGNK ; INLLGFLGLV ; HCLPCKDSCD ; 150: GVECGPGKAC ; RMLGGRPRCE ; CAPDCSGLPA ; RLQVCGSDGA ; TYRDECELRA ; 200: ARCRGHPDLS ; VMYRGRCRKS ; CEHVVCPRPQ ; SCVVDQTGSA ; HCVVCRAAPC ; 250: PVPSSPGQEL ; CGNNNVTYIS ; SCHMRQATCF ; LGRSIGVRHA ; GSCAGTPEEP ; 263: PGGESAEEEE ; NFV
Sequence Length	263
String	O95633
Sub Unit	Interacts with INHBA and INHBB. Interacts with FN1. Interacts with ADAM12. Isoform 2 interacts with MLLT10; the interaction enhances MLLT10 in vitro transcriptional activity and self-association. Interacts with MSTN.

Uniprot	O95633
Gene Name	FSTL3
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:10272
Unigene	Hs.529038

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SKU	Supplier No.	Size	Your price	Quantity
BHE13812138	E0127h	96T	$536		Add to Cart

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