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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Endoribonuclease Dicer

SKU : BHE13803414

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0156h
Alternative Names	Helicase with RNase motif ; Helicase MOI ; DICER ; HERNA ; KIAA0928
Categories	Elisa
Function	Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto EIF2C2/AGO2. EIF2C2/AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. Also cleaves double-stranded RNA to produce short interfering RNAs (siRNAs) which target the selective destruction of complementary RNAs.
Specificity	Natural and recombinant Human Endoribonuclease Dicer
Subcellular Location	Cytoplasm
Detection Range	0.312-20ng/mL
Entryname	DICER_HUMAN
Method Type	Sandwich
Platform	PF00270
Protein Name	Endoribonuclease Dicer
Sensitivity	0.11ng/mL
Sequence	50: MKSPALQPLS ; MAGLQLMTPA ; SSPMGPFFGL ; PWQQEAIHDN ; IYTPRKYQVE ; 100: LLEAALDHNT ; IVCLNTGSGK ; TFIAVLLTKE ; LSYQIRGDFS ; RNGKRTVFLV ; 150: NSANQVAQQV ; SAVRTHSDLK ; VGEYSNLEVN ; ASWTKERWNQ ; EFTKHQVLIM ; 200: TCYVALNVLK ; NGYLSLSDIN ; LLVFDECHLA ; ILDHPYREIM ; KLCENCPSCP ; 250: RILGLTASIL ; NGKCDPEELE ; EKIQKLEKIL ; KSNAETATDL ; VVLDRYTSQP ; 300: CEIVVDCGPF ; TDRSGLYERL ; LMELEEALNF ; INDCNISVHS ; KERDSTLISK ; 350: QILSDCRAVL ; VVLGPWCADK ; VAGMMVRELQ ; KYIKHEQEEL ; HRKFLLFTDT ; 400: FLRKIHALCE ; EHFSPASLDL ; KFVTPKVIKL ; LEILRKYKPY ; ERQQFESVEW ; 450: YNNRNQDNYV ; SWSDSEDDDE ; DEEIEEKEKP ; ETNFPSPFTN ; ILCGIIFVER ; 500: RYTAVVLNRL ; IKEAGKQDPE ; LAYISSNFIT ; GHGIGKNQPR ; NKQMEAEFRK ; 550: QEEVLRKFRA ; HETNLLIATS ; IVEEGVDIPK ; CNLVVRFDLP ; TEYRSYVQSK ; 600: GRARAPISNY ; IMLADTDKIK ; SFEEDLKTYK ; AIEKILRNKC ; SKSVDTGETD ; 650: IDPVMDDDDV ; FPPYVLRPDD ; GGPRVTINTA ; IGHINRYCAR ; LPSDPFTHLA ; 700: PKCRTRELPD ; GTFYSTLYLP ; INSPLRASIV ; GPPMSCVRLA ; ERVVALICCE ; 750: KLHKIGELDD ; HLMPVGKETV ; KYEEELDLHD ; EEETSVPGRP ; GSTKRRQCYP ; 800: KAIPECLRDS ; YPRPDQPCYL ; YVIGMVLTTP ; LPDELNFRRR ; KLYPPEDTTR ; 850: CFGILTAKPI ; PQIPHFPVYT ; RSGEVTISIE ; LKKSGFMLSL ; QMLELITRLH ; 900: QYIFSHILRL ; EKPALEFKPT ; DADSAYCVLP ; LNVVNDSSTL ; DIDFKFMEDI ; 950: EKSEARIGIP ; STKYTKETPF ; VFKLEDYQDA ; VIIPRYRNFD ; QPHRFYVADV ; 1000: YTDLTPLSKF ; PSPEYETFAE ; YYKTKYNLDL ; TNLNQPLLDV ; DHTSSRLNLL ; 1050: TPRHLNQKGK ; ALPLSSAEKR ; KAKWESLQNK ; QILVPELCAI ; HPIPASLWRK ; 1100: AVCLPSILYR ; LHCLLTAEEL ; RAQTASDAGV ; GVRSLPADFR ; YPNLDFGWKK ; 1150: SIDSKSFISI ; SNSSSAENDN ; YCKHSTIVPE ; NAAHQGANRT ; SSLENHDQMS ; 1200: VNCRTLLSES ; PGKLHVEVSA ; DLTAINGLSY ; NQNLANGSYD ; LANRDFCQGN ; 1250: QLNYYKQEIP ; VQPTTSYSIQ ; NLYSYENQPQ ; PSDECTLLSN ; KYLDGNANKS ; 1300: TSDGSPVMAV ; MPGTTDTIQV ; LKGRMDSEQS ; PSIGYSSRTL ; GPNPGLILQA ; 1350: LTLSNASDGF ; NLERLEMLGD ; SFLKHAITTY ; LFCTYPDAHE ; GRLSYMRSKK ; 1400: VSNCNLYRLG ; KKKGLPSRMV ; VSIFDPPVNW ; LPPGYVVNQD ; KSNTDKWEKD ; 1450: EMTKDCMLAN ; GKLDEDYEEE ; DEEEESLMWR ; APKEEADYED ; DFLEYDQEHI ; 1500: RFIDNMLMGS ; GAFVKKISLS ; PFSTTDSAYE ; WKMPKKSSLG ; SMPFSSDFED ; 1550: FDYSSWDAMC ; YLDPSKAVEE ; DDFVVGFWNP ; SEENCGVDTG ; KQSISYDLHT ; 1600: EQCIADKSIA ; DCVEALLGCY ; LTSCGERAAQ ; LFLCSLGLKV ; LPVIKRTDRE ; 1650: KALCPTRENF ; NSQQKNLSVS ; CAAASVASSR ; SSVLKDSEYG ; CLKIPPRCMF ; 1700: DHPDADKTLN ; HLISGFENFE ; KKINYRFKNK ; AYLLQAFTHA ; SYHYNTITDC ; 1750: YQRLEFLGDA ; ILDYLITKHL ; YEDPRQHSPG ; VLTDLRSALV ; NNTIFASLAV ; 1800: KYDYHKYFKA ; VSPELFHVID ; DFVQFQLEKN ; EMQGMDSELR ; RSEEDEEKEE ; 1850: DIEVPKAMGD ; IFESLAGAIY ; MDSGMSLETV ; WQVYYPMMRP ; LIEKFSANVP ; 1900: RSPVRELLEM ; EPETAKFSPA ; ERTYDGKVRV ; TVEVVGKGKF ; KGVGRSYRIA ; 1922: KSAAARRALR ; SLKANQPQVP ; NS
Sequence Length	1922
String	Q9UPY3
Sub Unit	Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC. Interacts with DHX9, EIF2C1, PIWIL1 and PRKRA. Associates with the 60S ribosome.

Uniprot	Q9UPY3
Gene Name	DICER1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:23405
Unigene	Hs.87889

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SKU	Supplier No.	Size	Your price	Quantity
BHE13803414	E0156h	96T	$736		Add to Cart

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