JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
orders@biohippo.com

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Human Double-stranded RNA-specific adenosine deaminase

SKU : BHE13803404

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E10803h
Alternative Names	136 kDa double-stranded RNA-binding protein ; p136 ; Interferon-inducible protein 4 ; IFI-4 ; K88DSRBP ; ADAR1 ; DSRAD ; G1P1 ; IFI4
Categories	Elisa
Function	Converts multiple adenosines to inosines and creates I/U mismatched base pairs in double-helical RNA substrates without apparent sequence specificity. Has been found to modify more frequently adenosines in AU-rich regions, probably due to the relative ease of melting A/U base pairs as compared to G/C pairs. Functions to modify viral RNA genomes and may be responsible for hypermutation of certain negative-stranded viruses. Edits the messenger RNAs for glutamate receptor (GLUR) subunits by site-selective adenosine deamination. Produces low-level editing at the GLUR-B Q/R site, but edits efficiently at the R/G site and HOTSPOT1. Binds to short interfering RNAs (siRNA) without editing them and suppresses siRNA-mediated RNA interference. Binds to ILF3/NF90 and up-regulates ILF3-mediated gene expression.
Specificity	Natural and recombinant Human Double-stranded RNA-specific adenosine deaminase
Subcellular Location	Cytoplasm Nucleus nucleolus Isoform 1 is found predominantly in cytoplasm but appears to shuttle between the cytoplasm and nucleus. Isoform 5 is found exclusively in the nucleolus.
Detection Range	0.312-20ng/mL
Entryname	DSRAD_HUMAN
Method Type	Sandwich
Platform	PF02137
Protein Name	Double-stranded RNA-specific adenosine deaminase
Sensitivity	0.182ng/mL
Sequence	50: MNPRQGYSLS ; GYYTHPFQGY ; EHRQLRYQQP ; GPGSSPSSFL ; LKQIEFLKGQ ; 100: LPEAPVIGKQ ; TPSLPPSLPG ; LRPRFPVLLA ; SSTRGRQVDI ; RGVPRGVHLR ; 150: SQGLQRGFQH ; PSPRGRSLPQ ; RGVDCLSSHF ; QELSIYQDQE ; QRILKFLEEL ; 200: GEGKATTAHD ; LSGKLGTPKK ; EINRVLYSLA ; KKGKLQKEAG ; TPPLWKIAVS ; 250: TQAWNQHSGV ; VRPDGHSQGA ; PNSDPSLEPE ; DRNSTSVSED ; LLEPFIAVSA ; 300: QAWNQHSGVV ; RPDSHSQGSP ; NSDPGLEPED ; SNSTSALEDP ; LEFLDMAEIK ; 350: EKICDYLFNV ; SDSSALNLAK ; NIGLTKARDI ; NAVLIDMERQ ; GDVYRQGTTP ; 400: PIWHLTDKKR ; ERMQIKRNTN ; SVPETAPAAI ; PETKRNAEFL ; TCNIPTSNAS ; 450: NNMVTTEKVE ; NGQEPVIKLE ; NRQEARPEPA ; RLKPPVHYNG ; PSKAGYVDFE ; 500: NGQWATDDIP ; DDLNSIRAAP ; GEFRAIMEMP ; SFYSHGLPRC ; SPYKKLTECQ ; 550: LKNPISGLLE ; YAQFASQTCE ; FNMIEQSGPP ; HEPRFKFQVV ; INGREFPPAE ; 600: AGSKKVAKQD ; AAMKAMTILL ; EEAKAKDSGK ; SEESSHYSTE ; KESEKTAESQ ; 650: TPTPSATSFF ; SGKSPVTTLL ; ECMHKLGNSC ; EFRLLSKEGP ; AHEPKFQYCV ; 700: AVGAQTFPSV ; SAPSKKVAKQ ; MAAEEAMKAL ; HGEATNSMAS ; DNQPEGMISE ; 750: SLDNLESMMP ; NKVRKIGELV ; RYLNTNPVGG ; LLEYARSHGF ; AAEFKLVDQS ; 800: GPPHEPKFVY ; QAKVGGRWFP ; AVCAHSKKQG ; KQEAADAALR ; VLIGENEKAE ; 850: RMGFTEVTPV ; TGASLRRTML ; LLSRSPEAQP ; KTLPLTGSTF ; HDQIAMLSHR ; 900: CFNTLTNSFQ ; PSLLGRKILA ; AIIMKKDSED ; MGVVVSLGTG ; NRCVKGDSLS ; 950: LKGETVNDCH ; AEIISRRGFI ; RFLYSELMKY ; NSQTAKDSIF ; EPAKGGEKLQ ; 1000: IKKTVSFHLY ; ISTAPCGDGA ; LFDKSCSDRA ; MESTESRHYP ; VFENPKQGKL ; 1050: RTKVENGEGT ; IPVESSDIVP ; TWDGIRLGER ; LRTMSCSDKI ; LRWNVLGLQG ; 1100: ALLTHFLQPI ; YLKSVTLGYL ; FSQGHLTRAI ; CCRVTRDGSA ; FEDGLRHPFI ; 1150: VNHPKVGRVS ; IYDSKRQSGK ; TKETSVNWCL ; ADGYDLEILD ; GTRGTVDGPR ; 1200: NELSRVSKKN ; IFLLFKKLCS ; FRYRRDLLRL ; SYGEAKKAAR ; DYETAKNYFK ; 1226: KGLKDMGYGN ; WISKPQEEKN ; FYLCPV
Sequence Length	1226
String	P55265
Sub Unit	Homodimer. Isoform 1 interacts with ILF2/NF45 and ILF3/NF90.

Uniprot	P55265
Gene Name	ADAR
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:103
Unigene	Hs.12341

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13803404	E10803h	96T	$736		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.