ELISA Kit for Human Dickkopf-related protein 3

Mfr.No.	E6373h
Alternative Names	REIC ; UNQ258/PRO295
Categories	Elisa
Function	Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a teary complex with the transmembrane protein KREMEN that promotes intealization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patteing, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Specificity	Natural and recombinant Human Dickkopf-related protein 3
Subcellular Location	Secreted
Detection Range	62.5-4000pg/mL
Entryname	DKK3_HUMAN
Method Type	Sandwich
Platform	PF04706
Protein Name	Dickkopf-related protein 3
Sensitivity	20pg/mL
Sequence	50: MQRLGATLLC ; LLLAAAVPTA ; PAPAPTATSA ; PVKPGPALSY ; PQEEATLNEM ; 100: FREVEELMED ; TQHKLRSAVE ; EMEAEEAAAK ; ASSEVNLANL ; PPSYHNETNT ; 150: DTKVGNNTIH ; VHREIHKITN ; NQTGQMVFSE ; TVITSVGDEE ; GRRSHECIID ; 200: EDCGPSMYCQ ; FASFQYTCQP ; CRGQRMLCTR ; DSECCGDQLC ; VWGHCTKMAT ; 250: RGSNGTICDN ; QRDCQPGLCC ; AFQRGLLFPV ; CTPLPVEGEL ; CHDPASRLLD ; 300: LITWELEPDG ; ALDRCPCASG ; LLCQPHSHSL ; VYVCKPTFVG ; SRDQDGEILL ; 350:
Sequence Length	350
String	Q9UBP4
Sub Unit	Interacts with LRP5 and LRP6.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13803729	E6373h	96T	$736		Add to Cart