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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Dachshund homolog 1

SKU : BHE13803438

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E2628h
Alternative Names	DACH
Categories	Elisa
Function	Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter (By similarity). Inhibits TGF-beta signaling through interaction with SMAD4 and NCOR1. Binds to chromatin DNA via its DACHbox-N domain.
Specificity	Natural and recombinant Human Dachshund homolog 1
Subcellular Location	Nucleus
Detection Range	0.312-20ng/mL
Entryname	DACH1_HUMAN
Method Type	Sandwich
Platform	PF02437
Protein Name	Dachshund homolog 1
Sensitivity	0.188ng/mL
Sequence	50: MAVPAALIPP ; TQLVPPQPPI ; STSASSSGTT ; TSTSSATSSP ; APSIGPPASS ; 100: GPTLFRPEPI ; ASAAAAAATV ; TSTGGGGGGG ; GSGGGGGSSG ; NGGGGGGGGG ; 150: GSNCNPNLAA ; ASNGSGGGGG ; GISAGGGVAS ; STPINASTGS ; SSSSSSSSSS ; 200: SSSSSSSSSS ; SSSCGPLPGK ; PVYSTPSPVE ; NTPQNNECKM ; VDLRGAKVAS ; 250: FTVEGCELIC ; LPQAFDLFLK ; HLVGGLHTVY ; TKLKRLEITP ; VVCNVEQVRI ; 300: LRGLGAIQPG ; VNRCKLISRK ; DFETLYNDCT ; NASSRPGRPP ; KRTQSVTSPE ; 350: NSHIMPHSVP ; GLMSPGIIPP ; TGLTAAAAAA ; AAATNAAIAE ; AMKVKKIKLE ; 400: AMSNYHASNN ; QHGADSENGD ; MNSSVGSSDG ; SWDKETLPSS ; PSQGPQASIT ; 450: HPRMPGARSL ; PLSHPLNHLQ ; QSHLLPNGLE ; LPFMMMPHPL ; IPVSLPPASV ; 500: TMAMSQMNHL ; STIANMAAAA ; QVQSPPSRVE ; TSVIKERVPD ; SPSPAPSLEE ; 550: GRRPGSHPSS ; HRSSSVSSSP ; ARTESSSDRI ; PVHQNGLSMN ; QMLMGLSPNV ; 600: LPGPKEGDLA ; GHDMGHESKR ; MHIEKDETPL ; STPTARDSLD ; KLSLTGHGQP ; 650: LPPGFPSPFL ; FPDGLSSIET ; LLTNIQGLLK ; VAIDNARAQE ; KQVQLEKTEL ; 700: KMDFLREREL ; RETLEKQLAM ; EQKNRAIVQK ; RLKKEKKAKR ; KLQEALEFET ; 750: KRREQAEQTL ; KQAASTDSLR ; VLNDSLTPEI ; EADRSGGRTD ; AERTIQDGRL ; 758: YLKTTVMY
Sequence Length	758
String	Q9UI36
Sub Unit	Interacts with SIX1, SIX6 and EYA3. Interacts with NCOR1 and HDAC3 through its N-terminus. Interacts with SIN3A through its C-terminus (By similarity). Interacts with SMAD3 and SMAD4.

Uniprot	Q9UI36
Gene Name	DACH1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:1602
Unigene	Hs.129452

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SKU	Supplier No.	Size	Your price	Quantity
BHE13803438	E2628h	96T	$736		Add to Cart

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