Protein-glutamine gamma-glutamyltransferase A chain ; Transglutaminase A chain ; F13A
Categories
Elisa
Function
Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
Specificity
Natural and recombinant Human Coagulation factor XIII A chain
Subcellular Location
Cytoplasm Secreted Secreted into the blood plasma. Cytoplasmic in most tissues, but also secreted in the blood plasma.