17-beta-hydroxysteroid dehydrogenase 10 ; 17-beta-HSD 10 ; 1.1.1.51 ; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase ; 1.1.1.178 ; 3-hydroxyacyl-CoA dehydrogenase type II ; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein ; Mitochondrial ribonuclease P protein 2 ; Mitochondrial RNase P protein 2 ; Short chain dehydrogenase/reductase family 5C member 1 ; Short-chain type dehydrogenase/reductase XH98G2 ; Type II HADH ;
Categories
Elisa
Function
Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
Specificity
Natural and recombinant Human 3-hydroxyacyl-CoA dehydrogenase type-2