ELISA Kit for Bovine Pigment epithelium-derived factor

Mfr.No.	E0784b
Alternative Names	Serpin F1 ; PEDF
Categories	Elisa
Function	Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Specificity	Natural and recombinant Bovine Pigment epithelium-derived factor
Subcellular Location	Secreted Melanosome
Detection Range	7.8-500ng/ml
Entryname	PEDF_BOVIN
Method Type	Sandwich
Platform	PF00079
Protein Name	Pigment epithelium-derived factor
Sensitivity	3.5ng/ml
Sequence	50: MQALVLLLWT ; GALLGFGRCQ ; NAGQEAGSLT ; PESTGAPVEE ; EDPFFKVPVN ; 100: KLAAAVSNFG ; YDLYRVRSGE ; SPTANVLLSP ; LSVATALSAL ; SLGAEQRTES ; 150: NIHRALYYDL ; ISNPDIHGTY ; KDLLASVTAP ; QKNLKSASRI ; IFERKLRIKA ; 200: SFIPPLEKSY ; GTRPRILTGN ; SRVDLQEINN ; WVQAQMKGKV ; ARSTREMPSE ; 250: ISIFLLGVAY ; FKGQWVTKFD ; SRKTSLEDFY ; LDEERTVKVP ; MMSDPQAVLR ; 300: YGLDSDLNCK ; IAQLPLTGST ; SIIFFLPQKV ; TQNLTLIEES ; LTSEFIHDID ; 350: RELKTVQAVL ; TIPKLKLSYE ; GELTKSVQEL ; KLQSLFDAPD ; FSKITGKPIK ; 400: LTQVEHRVGF ; EWNEDGAGTN ; SSPGVQPARL ; TFPLDYHLNQ ; PFIFVLRDTD ; 416: TGALLFIGKI ; LDPRGT
Sequence Length	416
String	Q95121

Reference	1. Perez-Mediavilla L., Chew C., Campochiaro P., Zack D.J., Becerra S.P. Submitted (1996-11) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Retinal pigment epithelium. 2. Singh V.K., Chader G.J., Rodriguez I.R. Submitted (1997-08) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 3. NIH - Mammalian Gene Collection (MGC) project Submitted (2006-01) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Hereford. tissue: Testis. 4. "Pigment epithelium-derived factor behaves like a noninhibitory serpin. Neurotrophic activity does not require the serpin reactive loop." Becerra S.P., Sagasti A., Spinella P., Notario V. J. Biol. Chem.270:25992-25999(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-47 AND 380-399 tissue: Eye.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13812218	E0784b	96T	$900		Add to Cart