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ELISA Kit for Human Glycoprotein hormones alpha chain

SKU : BHE13804066

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0441h
Alternative Names	Anterior pituitary glycoprotein hormones common subunit alpha ; Choriogonadotropin alpha chain ; Chorionic gonadotrophin subunit alpha ; CG-alpha ; Follicle-stimulating hormone alpha chain ; FSH-alpha ; Follitropin alpha chain ; Luteinizing hormone alpha chain ; LSH-alpha ; Lutropin alpha chain ; Thyroid-stimulating hormone alpha chain ; TSH-alpha ; Thyrotropin alpha chain
Categories	Elisa
Specificity	Natural and recombinant Human Glycoprotein hormones alpha chain
Subcellular Location	Secreted
Detection Range	3.75-240mIU/mL
Entryname	GLHA_HUMAN
Method Type	Sandwich
Platform	PF00236
Protein Name	Glycoprotein hormones alpha chain
Sensitivity	1.4mIU/mL
Sequence	50: MDYYRKYAAI ; FLVTLSVFLH ; VLHSAPDVQD ; CPECTLQENP ; FFSQPGAPIL ; 100: QCMGCCFSRA ; YPTPLRSKKT ; MLVQKNVTSE ; STCCVAKSYN ; RVTVMGGFKV ; 116: ENHTACHCST ; CYYHKS
Sequence Length	116
String	P01215
Sub Unit	Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.

Uniprot	P01215
Gene Name	CGA
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:1081
Unigene	Hs.119689

Reference	1. "Isolation, cloning and sequence analysis of the cDNA for the alpha-subunit of human chorionic gonadotropin." Fiddes J.C., Goodman H.M. Nature281:351-356(1979) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] 2. "Structure and regulation of human thyroid-stimulating hormone (TSH) gene." Miyoshi I., Kasai N., Hayashizaki Y. Nippon Rinsho52:940-947(1994) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] 3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Placenta. 4. "The gene encoding the common alpha subunit of the four human glycoprotein hormones." Fiddes J.C., Goodman H.M. J. Mol. Appl. Genet.1:3-18(1981) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-98 5. "The amino acid sequences of the prepeptides contained in the alpha and beta subunits of human choriogonadotropin." Birken S., Fetherston J., Canfield R.E., Boime I. J. Biol. Chem.256:1816-1823(1981) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-24 6. "Human pituitary thyrotropin. The primary structure of the alpha and beta subunits." Sairam M.R., Li C.H. Can. J. Biochem.55:755-760(1977) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 28-116 7. "Human pituitary interstitial cell stimulating hormone: primary structure of the alpha-subunit." Sairam M.R., Papkoff H., Li C.H. Biochem. Biophys. Res. Commun.48:530-537(1972) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 28-116 8. "Structure of human luteninizing hormone." Keutmann H.T., Williams R.M., Bishop W.H., Ryan R.J. Fed. Proc.37:1828-1828(1978) [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE;SEQUENCE REVISION 9. "Primary amino acid sequence of follicle-stimulating hormone from human pituitary glands. I. alpha subunit." Rathnam P., Saxena B.B. J. Biol. Chem.250:6735-6746(1975) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-116 tissue: Pituitary. 10. "Human follicle stimulating hormone (hFSH): first proposal for the amino acid sequence of the alpha-subunit (hFSHa) and first demonstration of its identity with the alpha-subunit of human luteinizing hormone (hLHa)." Shome B., Parlow A.F. J. Clin. Endocrinol. Metab.39:199-202(1974) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 28-116 11. "The amino acid sequence of human chorionic gonadotropin. The alpha subunit and beta subunit." Morgan F.J., Birken S., Canfield R.E. J. Biol. Chem.250:5247-5258(1975) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-116 12. "Human chorionic gonadotropin. Linear amino acid sequence of the alpha subunit." Bellisario R., Carlsen R.B., Bahl O.P. J. Biol. Chem.248:6796-6809(1973) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-116 13. "Studies on the disulfide bonds in human pituitary follicle-stimulating hormone." Fujiki Y., Rathnam P., Saxena B.B. Biochim. Biophys. Acta624:428-435(1980) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PRELIMINARY ASSIGNMENT OF DISULFIDE BONDS 14. "Assignment of disulfide bonds in the alpha subunit of human chorionic gonadotropin." Mise T., Bahl O.P. J. Biol. Chem.255:8516-8522(1980) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PRELIMINARY ASSIGNMENT OF DISULFIDE BONDS 15. "NMR investigations of the N-linked oligosaccharides at individual glycosylation sites of human lutropin." Weisshaar G., Hiyama J., Renwick A.G.C., Nimtz M. Eur. J. Biochem.195:257-268(1991) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE OF CARBOHYDRATES 16. "Crystal structure of human chorionic gonadotropin." Laptho A.J., Harris D.C., Littlejohn A., Lustbader J.W., Canfield R.E., Machin K.J., Morgan F.J., Isaacs N.W. Nature369:455-461(1994) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) 17. "NMR studies of the free alpha subunit of human chorionic gonadotropin. Structural influences of N-glycosylation and the beta subunit on the conformation of the alpha subunit." de Beer T., van Zuylen C.W.E.M., Leeflang B.R., Haard K., Boelens R., Kaptein R., Kamerling J.P., Vliegenthart J.F.G. Eur. J. Biochem.241:229-242(1996) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR 18. "Structure of human follicle-stimulating hormone in complex with its receptor." Fan Q.R., Hendrickson W.A. Nature433:269-277(2005) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.92 ANGSTROMS) OF 25-116 IN COMPLEX WITH FSHB AND FSHR;DISULFIDE BONDS;GLYCOSYLATION AT ASN-76 AND ASN-102

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