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Rat Interleukin 1 Beta - IL-1B ELISA Kit

BHE12111437

IL-1? is a member of the interleukin 1 family of cytokines. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

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Gene ID 373606
UniProt ID Q63264
Antigen IL1B
Research Area Immunology
Protocol These standard curves of E0119Ra are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
40ng/ml 2.03 2.053 1.995
2.076
20ng/ml 1.56 1.576 1.518
1.592
10ng/ml 1.004 0.945 0.887
0.887
5ng/ml 0.479 0.474 0.416
0.47
2.5ng/ml 0.253 0.259 0.2
0.264
0ng/ml 0.06 0.0581 0
0.056
Precision We measured random samples of E0119Ra within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 8.8 0.39 4.4
Intra-Assay 2 18 17.5 0.75 4.3
Intra-Assay 3 18 5.5 0.26 4.8
Storage 2-8°C
Reference
Synergistic Effect of Omega-3 and Probiotic Supplementation on Preventing Ligature-Induced Periodontitis
Journal: Probiotics Antimicrob Proteins. 2022 Feb;14(1):114-120
Omarigliptin attenuates rotenone-induced Parkinson's disease in rats: Possible role of oxidative stress, endoplasmic reticulum stress and immune modulation
Journal: Food Chem Toxicol. 2022 Jun;164:113015
Neuroprotective effect of bone marrow-derived mesenchymal stem cell secretome in 6-OHDA-induced Parkinson's disease
Journal: Regen Med. 2021 Oct;16(10):915-930
Febuxostat attenuates vascular calcification induced by vitamin D3 plus nicotine in rats
Journal: Eur J Pharm Sci. 2021 Jan 1;156:105580
Basal Blood Morphology, Serum Biochemistry, and the Liver and Muscle Structure of Weaned Wistar Rats Prenatally Exposed to Fumonisins
Journal: Animals (Basel). 2022 Sep 8;12(18):2353
Synergistic Effect of Omega-3 and Probiotic Supplementation on Preventing Ligature-Induced Periodontitis
Journal: Probiotics Antimicrob Proteins. 2022 Feb;14(1):114-120.
Omarigliptin attenuates rotenone-induced Parkinson's disease in rats: Possible role of oxidative stress, endoplasmic reticulum stress and immune modulation
Journal: Food Chem Toxicol. 2022 Jun;164:113015.
Febuxostat attenuates vascular calcification induced by vitamin D3 plus nicotine in rats
Journal: Eur J Pharm Sci. 2021 Jan 1;156:105580.
Basal Blood Morphology, Serum Biochemistry, and the Liver and Muscle Structure of Weaned Wistar Rats Prenatally Exposed to Fumonisins
Journal: Animals (Basel). 2022 Sep 8;12(18):2353.
Dietary polyvinyl alcohol and alginate nanofibers ameliorate hyperglycemia by reducing insulin and glucose-metabolizing enzyme levels in rats with streptozotocin-induced diabetes
Journal: Vet World. 2021 Apr;14(4):847-853.
HMGB1, NLRP3, IL-6 and ACE2 levels are elevated in COVID-19 with headache: a window to the infection-related headache mechanism
Journal: J Headache Pain. 2021 Aug 12;22(1):94.
SKU Supplier No. Size Your price Quantity
BHE12111437 E0119Ra 48T $320
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BHE12111437 E0119Ra 96T $458
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