Mouse Tyrosine-protein Phosphatase Non-receptor Type 4

Mfr.No.

E2548Mo

Alternative Names

PTPN 4;PTPN4;Testis-enriched protein tyrosine phosphatase;Tyrosine-protein phosphatase non-receptor type 4

Reactivity

Mouse

Detection Range

2-600ng/L

Sample Type

Serum, Plasma, Cell culture supernatants

Assay Type

Sandwich

Assay Duration

1h 30m

Molecular Weight

105832

Kit Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Sensitivity

1.27ng/L

Background

Phosphatase that plays a role in immunity, learning, synaptic plasticity or cell homeostasis (PubMed: 17953619, PubMed: 25825441). Regulates neuronal cell homeostasis by protecting neurons against apoptosis (By similarity). Negatively regulates TLR4-induced interferon beta production by dephosphorylating adapter TICAM2 and inhibiting subsequent TRAM-TRIF interaction (PubMed: 25825441). Dephosphorylates also the immunoreceptor tyrosine-based activation motifs/ITAMs of the TCR zeta subunit and thereby negatively regulates TCR-mediated signaling pathway (PubMed: 18614237). May act at junctions between the membrane and the cytoskeleton.

Gene ID	19258
UniProt ID	Q9WU22
Antigen	PTPN4

Research Area

Others

Protocol

These standard curves of E2548Mo are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
320ng/L	2.072	2.171	2.138
	2.271
160ng/L	1.145	1.221	1.187
	1.296
80ng/L	0.706	0.759	0.726
	0.812
40ng/L	0.448	0.423	0.39
	0.399
20ng/L	0.19	0.215	0.182
	0.24
0ng/L	0.024	0.033	0
	0.042

Precision

We measured random samples of E2548Mo within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	106.7	6.35	5.9
Intra-Assay	2	18	241.7	7.99	3.3
Intra-Assay	3	18	41.4	2.23	5.4

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12110359	E2548Mo	48T	$320		Add to Cart
BHE12110359	E2548Mo	96T	$458		Add to Cart

Mouse Tyrosine-protein Phosphatase Non-receptor Type 4 - PTPN4 ELISA Kit

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