Mouse Tumor Necrosis Factor Receptor Superfamily Member 10B

Mfr.No.

E2536Mo

Alternative Names

CD antigen CD262;Death receptor 5;DR;DR5;KI;Kille;KILLER;Ly9;Ly98;MK;TNFRSF10B;TR;TRAILR2;TRIC;TRICK;TRICK2A;TRICK2B;TRICKB;Tumor necrosis factor receptor superfamily member 10B

Reactivity

Mouse

Detection Range

0.3-90ng/mL

Sample Type

Serum, Plasma, Cell culture supernatants

Assay Type

Sandwich

Assay Duration

1h 30m

Molecular Weight

42165

Kit Components

Components	Quantity
Pre-coated ELISA plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Sensitivity

0.124ng/mL

Background

Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.

Gene ID	21933
UniProt ID	Q9QZM4
Antigen	TNFRSF10B

Research Area

Cell Biology; Signal Transduction; Cancer; Cardiovascular

Protocol

These standard curves of E2536Mo are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
48ng/mL	2.168	2.103	2.056
	2.038
24ng/mL	1.364	1.379	1.332
	1.395
12ng/mL	0.649	0.652	0.605
	0.655
6ng/mL	0.445	0.453	0.406
	0.461
3ng/mL	0.213	0.168	0.12
	0.123
0ng/mL	0.048	0.048	0
	0.048

Precision

We measured random samples of E2536Mo within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	14.94	0.69	4.65
Intra-Assay	2	18	35.54	1.76	4.96
Intra-Assay	3	18	8.25	0.46	5.59

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12110347	E2536Mo	48T	$320		Add to Cart
BHE12110347	E2536Mo	96T	$458		Add to Cart

Mouse Tumor Necrosis Factor Receptor Superfamily Member 10B - TNFRSF10B ELISA Kit

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