Human Suppressor of Cytokine Signaling 6

Mfr.No.

E6234Hu

Alternative Names

CIS4;CIS-4;Cytokine-inducible SH2 protein 4;HSPC060;SOCS4;SOCS-4;SOCS6;SOCS-6;SSI4;STAI4;STATI4;Suppressor of cytokine signaling 4;Suppressor of cytokine signaling 6;

Reactivity

Human

Detection Range

10-2000ng/L

Sample Type

Serum, Plasma, Cell culture supernatants

Assay Type

Sandwich

Assay Duration

1h 30m

Molecular Weight

59528

Kit Components

Components	Quantity
Pre-coated ELISA plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Sensitivity

4.84ng/L

Background

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor.

Gene ID	9306
UniProt ID	O14544
Antigen	SOCS6

Research Area

Others

Protocol

These standard curves of E6234Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
1200ng/L	2.358	2.21	2.153
	2.062
600ng/L	1.384	1.351	1.294
	1.318
300ng/L	0.729	0.775	0.718
	0.821
150ng/L	0.42	0.457	0.4
	0.495
75ng/L	0.266	0.26	0.203
	0.253
0ng/L	0.063	0.057	0
	0.051

Precision

We measured random samples of E6234Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	248.64	14.05	5.65
Intra-Assay	2	18	387.55	15.39	3.97
Intra-Assay	3	18	565.5	18.17	3.21

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12107596	E6234Hu	48T	$320		Add to Cart
BHE12107596	E6234Hu	96T	$458		Add to Cart

Human Suppressor of Cytokine Signaling 6 - SOCS6 ELISA Kit

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