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Secreted cytokine-like protein (PubMed: 12847263). Binds to the scavenger receptor MARCO (PubMed: 12847263). Can also bind to pathogens including the Gram-positive bacterium L.monocytogenes, the Gram-negative bacterium P.aeruginosa, and yeast (PubMed: 12847263). Strongly inhibits phospholipase A2 (PLA2G1B) activity (PubMed: 24213919). Seems to have anti-inflammatory effects in respiratory epithelium (By similarity). Also has anti-fibrotic activity in lung (PubMed: 24213919). May play a role in fetal lung development and maturation (PubMed: 24213919). Promotes branching morphogenesis during early stages of lung development (PubMed: 24213919). In the pituitary, may inhibit production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) (By similarity).
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