Human Potassium Voltage-gated Channel Subfamily E Member 1

Mfr.No.

E4851Hu

Description

This sandwich kit is for the accurate quantitative detection of human Potassium Voltage-gated Channel Subfamily E Member 1 (also known as KCND1) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.

Alternative Names

Delayed rectifier potassium Channel subunit IsK;IKs producing slow voltage-gated potassium Channel subunit beta Mink;KCNE 1;KCNE1;Minimal potassium Channel;Potassium voltage-gated Channel subfamily E member 1

Reactivity

Human

Detection Range

20-3500ng/L

Sample Type

Serum, Plasma, Cell culture supernatants

Assay Type

Sandwich

Assay Duration

1h 30m

Molecular Weight

14675

Kit Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Sensitivity

10.55ng/L

Background

Ancillary protein that assembles as a beta subunit with a voltage-gated potassium Channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the Channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium Channel KCNB1 (PubMed: 19219384). Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) Channel. The outward current reaches its steady state only after 50 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr).

Gene ID	3753
UniProt ID	P15382
Antigen	KCNE1

Research Area

Others

Protocol

These standard curves of E4851Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
2000ng/L	2.164	2.079	2.037
	1.994
1000ng/L	1.052	1.031	0.99
	1.011
500ng/L	0.449	0.476	0.434
	0.503
250ng/L	0.212	0.187	0.146
	0.163
125ng/L	0.1	0.11	0.069
	0.12
0ng/L	0.05	0.041	0
	0.033

Precision

We measured random samples of E4851Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	532	23.81	4.5
Intra-Assay	2	18	1050.8	42.35	4
Intra-Assay	3	18	1298.4	34.84	2.7

Storage	2-8°C

Have you used this product?

Rate it now..!!

SKU	Supplier No.	Size	Your price	Quantity
BHE12106126	E4851Hu	48T	$320		Add to Cart
BHE12106126	E4851Hu	96T	$458		Add to Cart

Human Potassium Voltage-gated Channel Subfamily E Member 1 - KCNE1 ELISA Kit

Contact us to order

Tel

Email

Contact us to order

Tel

Email

Reviews of Human Potassium Voltage-gated Channel Subfamily E Member 1 - KCNE1 ELISA Kit

Rate it now..!!