Human Peptidyl-prolyl Cis-trans Isomerase Fkbp1A

Mfr.No.

E5844Hu

Alternative Names

12 kDa FK506-binding protein;12 kDa FKBP;Calstabin-1;FK506-binding protein 1A;FKBP 1A;FKBP-12;FKBP1A;FKBP-1A;Immunophilin FKBP12;Peptidyl-prolyl cis-trans isomerase FKBP1A;PPIase FKBP1A;Rotamase

Reactivity

Human

Detection Range

20-4500ng/L

Sample Type

Serum, Plasma, Cell culture supernatants

Assay Type

Sandwich

Assay Duration

1h 30m

Molecular Weight

11951

Kit Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Sensitivity

9.97ng/L

Background

Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruits SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium Channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic Peptide bonds in oligopeptides.

Gene ID	2280
UniProt ID	P62942
Antigen	FKBP1A

Research Area

Others

Protocol

These standard curves of E5844Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
2400ng/L	1.864	1.829	1.776
	1.793
1200ng/L	0.927	0.933	0.88
	0.939
600ng/L	0.41	0.484	0.431
	0.559
300ng/L	0.276	0.257	0.204
	0.238
150ng/L	0.138	0.113	0.06
	0.088
0ng/L	0.047	0.053	0
	0.06

Precision

We measured random samples of E5844Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	1323.7	66.33	5
Intra-Assay	2	18	2100.1	64.45	3.1
Intra-Assay	3	18	570.8	23.25	4.1

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12107206	E5844Hu	48T	$320		Add to Cart
BHE12107206	E5844Hu	96T	$458		Add to Cart

Human Peptidyl-prolyl Cis-trans Isomerase Fkbp1A - FKBP1A ELISA Kit

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