Human Kv Channel-interacting Protein 4

Mfr.No.

E3830Hu

Sensitivity

0.024ng/ml

Detection Range

0.05-30ng/ml

Reactivity

Human

Assay Duration

1h 30m

Assay Type

Sandwich

Description

This sandwich kit is for the accurate quantitative detection of human Kv Channel-interacting Protein 4 (also known as KCNIP4) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.

Alternative Names

A-type potassium Channel modulatory protein 4;CALP;Calsenilin-like protein;KCHIP4;KCNIP4;Kv Channel-interacting protein 4;Potassium Channel-interacting protein 4

Molecular Weight

28729

Kit Components

Components	Quantity
Pre-coated ELISA plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Precision

We measured random samples of E3830Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	15.35	0.42	2.72
Intra-Assay	2	18	5.36	0.29	5.43
Intra-Assay	3	18	3.05	0.18	5.83

Background

Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner (PubMed:11847232, PubMed:18957440, PubMed:23576435). Modulates KCND3/Kv4.3 currents (PubMed:23576435). Isoform 4 does not increase KCND2 expression at the cell membrane (PubMed:18957440). Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane.

Protocol

These standard curves of E3830Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
20ng/ml	2.265	2.298	2.239
	2.331
10ng/ml	1.169	1.181	1.122
	1.193
5ng/ml	0.854	0.752	0.693
	0.651
2.5ng/ml	0.46	0.49	0.431
	0.521
1.25ng/ml	0.247	0.238	0.179
	0.228
0ng/ml	0.059	0.059	0
	0.059

Gene ID	80333
UniProt ID	Q6PIL6

Research Area	Neuroscience

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12105275	E3830Hu	48T	$320		Add to Cart
BHE12105275	E3830Hu	96T	$458		Add to Cart

Human Kv Channel-interacting Protein 4 - KCNIP4 ELISA Kit

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