Human Integrin Alpha-2B - ITGA2B ELISA Kit

Mfr.No.

E5483Hu

Sensitivity

0.029ng/mL

Detection Range

0.05-20ng/mL

Reactivity

Human

Assay Duration

1h 30m

Assay Type

Sandwich

Alternative Names

CD antigen CD49b;CD49 antigen-like family member B;Collagen receptor;GPIa;Integrin alpha-2;ITGA 2;ITGA2;Platelet membrane glycoprotein Ia;VLA-2 subunit alpha;

Molecular Weight

129295

Kit Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Sample Type

Serum, Cell culture supernatants, Plasma

Precision

We measured random samples of E5483Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	3.7	0.14	3.7
Intra-Assay	2	18	7.4	0.26	3.4
Intra-Assay	3	18	2.9	0.13	4.4

Background

Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human rotavirus A. (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human echoviruses 1 and 8.

Protocol

These standard curves of E5483Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
12.8ng/mL	2.072	2.076	2.046
	2.079
6.4ng/mL	1.386	1.451	1.422
	1.516
3.2ng/mL	0.595	0.589	0.56
	0.582
1.6ng/mL	0.32	0.339	0.31
	0.358
0.8ng/mL	0.134	0.169	0.14
	0.205
0ng/mL	0.026	0.029	0
	0.032

Gene ID	3673
UniProt ID	P17301

Research Area	Signal Transduction

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12106845	E5483Hu	48T	$320		Add to Cart
BHE12106845	E5483Hu	96T	$458		Add to Cart

Human Integrin Alpha-2B - ITGA2B ELISA Kit

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