Human Growth Differentiation Factor 11

Mfr.No.

E2267Hu

Description

This sandwich kit is for the accurate quantitative detection of human Growth Differentiation Factor 11 (also known as GDF11) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.

Alternative Names

BMP-11;Bone morphogenetic protein 11;GDF 11;GDF11;GDF-11;Growth/differentiation factor 11

Reactivity

Human

Detection Range

10-3000ng/L

Sample Type

Serum, Plasma, Cell culture supernatants

Assay Type

Sandwich

Assay Duration

1h 30m

Molecular Weight

45091

Kit Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Sensitivity

5.76ng/L

Background

Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. May play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern (By similarity). Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3 (PubMed: 28257634).

Gene ID	10220
UniProt ID	O95390
Antigen	GDF11

Research Area

Signal Transduction

Protocol

These standard curves of E2267Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
1600ng/L	2.161	2.056	2.023
	1.951
800ng/L	1.395	1.394	1.362
	1.394
400ng/L	0.591	0.631	0.598
	0.671
200ng/L	0.445	0.411	0.379
	0.377
100ng/L	0.143	0.16	0.127
	0.176
0ng/L	0.037	0.033	0
	0.029

Precision

We measured random samples of E2267Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	207.7	10.06	4.8
Intra-Assay	2	18	868.8	36.64	4.2
Intra-Assay	3	18	540.1	27.46	5.1

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12103807	E2267Hu	48T	$320		Add to Cart
BHE12103807	E2267Hu	96T	$458		Add to Cart

Human Growth Differentiation Factor 11 - GDF11 ELISA Kit

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