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BHE12106698
Mitochondrial glutamate dehydrogenase that catalyzes the conversion of L-glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle (PubMed: 11032875, PubMed: 16959573, PubMed: 11254391, PubMed: 16023112). Plays a role in insulin homeostasis (PubMed: 9571255, PubMed: 11297618). May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity).
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