Human Formin-binding Protein 1

Mfr.No.

E3188Hu

Alternative Names

FNBP 1;FNBP1;Formin-binding protein 1;Formin-binding protein 17;hFBP17

Reactivity

Human

Detection Range

20-4500ng/L

Sample Type

Serum, Plasma, Cell culture supernatants

Assay Type

Sandwich

Assay Duration

1h 30m

Molecular Weight

71307

Kit Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Sensitivity

9.55ng/L

Background

May act as a link between RND2 signaling and regulation of the actin cytoskeleton (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during the late stage of clathrin-mediated endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also enhances actin polymerization via the recruitment of WASL/N-WASP, which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. May be required for the lysosomal retention of FASLG/FASL.

Gene ID	23048
UniProt ID	Q96RU3
Antigen	FNBP1

Research Area

Others

Protocol

These standard curves of E3188Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
2400ng/L	2.234	2.232	2.175
	2.229
1200ng/L	1.423	1.447	1.39
	1.471
600ng/L	0.744	0.794	0.737
	0.845
300ng/L	0.491	0.506	0.449
	0.52
150ng/L	0.27	0.3	0.243
	0.33
0ng/L	0.054	0.057	0
	0.06

Precision

We measured random samples of E3188Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	885.8	51.74	5.8
Intra-Assay	2	18	1164.7	36.03	3.1
Intra-Assay	3	18	385.6	27.56	7.1

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12104717	E3188Hu	48T	$320		Add to Cart
BHE12104717	E3188Hu	96T	$458		Add to Cart

Human Formin-binding Protein 1 - FNBP1 ELISA Kit

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