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BHE12105311
This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. [Isoform 2]: Activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
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