Human Bone Morphogenetic Protein Receptor 1A

Mfr.No.

E1564Hu

Sensitivity

0.045ng/mL

Detection Range

0.1-40ng/mL

Reactivity

Human

Assay Duration

1h 30m

Assay Type

Sandwich

Alternative Names

Activin receptor-like kinase 3;ALK-3;BMP type-1A receptor;BMPR 1A;BMPR1A;BMPR-1A;Bone morphogenetic protein receptor type-1A;CD antigen CD292;Serine/threonine-protein kinase receptor R5;SKR5

Molecular Weight

60198

Kit Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Sample Type

Serum, Cell culture supernatants, Plasma

Precision

We measured random samples of E1564Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	12.4	0.35	2.8
Intra-Assay	2	18	5.1	0.21	4.2
Intra-Assay	3	18	10.2	0.57	5.6

Background

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.

Protocol

These standard curves of E1564Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
24ng/mL	2.236	2.175	2.143
	2.114
12ng/mL	1.379	1.36	1.329
	1.341
6ng/mL	0.702	0.726	0.695
	0.751
3ng/mL	0.339	0.322	0.29
	0.305
1.5ng/mL	0.181	0.189	0.158
	0.198
0ng/mL	0.035	0.032	0
	0.028

Gene ID	657
UniProt ID	P36894

Research Area	Cardiovascular

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12103172	E1564Hu	48T	$320		Add to Cart
BHE12103172	E1564Hu	96T	$458		Add to Cart

Human Bone Morphogenetic Protein Receptor 1A - BMPR-1A ELISA Kit

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